Products & ReviewLife Sciences

Gilson Extractman Starter Kit

Gilson, Inc.22100000

The EXTRACTMAN ® Starter Kit allows you to be extracting in just minutes.

Gilson, Inc.

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Description

Make Your Lab as Smart as Your Science

EXTRACTMAN®, an innovative magnetic bead extraction platform, offers a faster and gentler approach to isolating target proteins from a variety of samples. EXTRACTMAN differs from traditional magnetic bead-based co-IP techniques by using Exclusion-based Sample Preparation (ESP™) technology, making it ideal for capturing weakly bound protein complexes without exposing them to high shear forces from pipette-based wash steps. Paired with non-porous magnetic beads, EXTRACTMAN enables high-yield, high-purity isolations without the need for long washing steps.

REMOVES PURIFICATION BOTTLENECKS

ESP™ magnetic bead technology purifies samples faster than other magnetic bead technologies by reducing the pipetting steps. The technology does not move liquids, but instead, beads are gently handled to protect sample integrity.

DISCOVERS WEAK AND TRANSIENT INTERACTIONS

Because analytes are magnetically extracted from samples without diluting, destroying, or otherwise disturbing the original sample, EXTRACTMAN is particularly efficient to discover difficult-to-capture interactions.

ERGONOMIC AND EASY TO USE

A simple slide of the handle isolates target proteins, which allows EXTRACTMAN to be used as a universal platform for a variety of commercial magnetic beads kits.

The EXTRACTMAN® Starter Kit allows you to be extracting in just minutes.

The EXTRACTMAN Starter Kit includes:

  • EXTRACTMAN Handle Assembly
  • EXTRACTMAN Base Assembly
  • Bead Collection Strips X 5
  • EXTRACTMAN 15 µL Extraction Plates X 5
  • EXTRACTMAN User's Guide
Application NoteLife Sciences

Expanded Analyte Isolation of Weakly- or Transiently-Bound Species through ESP™ and the Gilson EXTRACTMAN<sup>®</sup>

Most proteins perform their function through interaction with other molecules, including other proteins. These protein-protein complexes may occur constitutively or transiently with varying levels of affinity. Identifying the proteins that form these functional complexes may help researchers to understand a process or disease. One approach for identifying protein-protein interactions is co-immuno-precipitation (Co-IP). This application note describes how Gilson’s EXTRACTMAN® was used to isolate a previously undetected protein-protein complex.


Application NoteLife Sciences

The Gilson EXTRACTMAN<sup>®</sup> Delivers Rapid, Reproducible DNA Extraction with High Yield

DNA sequence analysis is an essential method in both research and diagnostics, with applications in a wide range of scientific fields. Effective and efficient sequence detection requires effective preparation methods. In this application note, Gilson’s EXTRACTMAN® was used to quickly, easily, and efficiently isolate DNA from crude preparations of mammalian and plant cells.


Application NoteGeneral Lab

EXTRACTMAN®: Rapid Yet Gentle Purification of Protein-Ligand Complexes

In this application note, Gilson present a new method demonstrating how the EXTRACTMAN can be used to capture Specific RNA partners of an RNA-binding protein without the need for cross-linking. The EXTRACTMAN can also be used to efficiently and specifically enrich endogenously expressed ribonucleoprotein complexes.


Application NoteSpectroscopy

PLATEMASTER® and EXTRACTMAN®: Rapid Enrichment and Clonal Selection of CRISPR Modified Cells

CRISPR is changing the face of how scientists are exploring new drug targets and uncovering how diseases work at the genetic level. However, as with any biological system, CRISPR is not 100% efficient, requiring screening to identify and isolate the cell or strain carrying the desired modification. EXTRACTMAN® enables rapid isolation of proteins that bind to an antibody-coated paramagnetic particle, and is a fast and efficient tool that can be used to enrich populations of CRISPR modified cells when an antigen based selection marker is used.

Introduction to the EXTRACTMAN Magnetic Bead Extraction Platform

Gilson’s EXTRACTMAN offers a quicker, more gentle magnetic mixing approach to isolating target proteins and is perfect for isolating elusive, weakly-bound protein complexes critical to protein interaction research. Save time by isolating up to 4 samples in parallel. Exclusion-based Sample Preparation (ESP™) technology isolates proteins while keeping the remaining sample intact for further study.


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