DRAQ7 by Biostatus Limited

Manufacturer Biostatus Limited  |   Model: DR70250  |  Available Worldwide
4.7
/
5.0
  |  18 reviews
A far-red viability dye staining nuclei in dead / apoptotic cells.


DRAQ7 by Biostatus Limited product image
DRAQ7
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Average Rating: 4.7
18 Scientists have reviewed this product

5 out of 5
Ease of use
5 out of 5
After sales service
5 out of 5
Value for money


Easy way to add valuable data to all our experiments
Rating: 5.0

  • Application Area: Monitor cell viability

"Great value, straightforward way to assess cell viability through flow cytometry in all our experimental settings. Easily incorporated into the work flow to provide robust and easy to interpret data."

Review date: 01 Dec 2017 | DRAQ7
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Flow Cytometry Core Facility, Blizard Institute, Queen Mary London University of London, UK



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Very bright photostable far red dye
Rating: 5.0

  • Application Area:Flow Cytometry

"The dye was easily loaded into cells at 37C giving a high level of fluorescence at 760 nm making it easy to gate out dead cells on flow cytometric dot-plots. There was no apparent photo-bleaching of this far red dye either, quite impressive."

Review date: 30 Nov 2017 | DRAQ7
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: Swansea University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Quality product, good value for money
Rating: 5.0

  • Application Area:Immunometabolism

"Very easy to use, gives clear, consistent and reproducible results, which makes measuring cell death easy and reliable. Would strongly recommend this product for measuring apoptosis. Good value for money."

Review date: 26 Nov 2017 | DRAQ7
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: Institut Cochin



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Great result
Rating: 4.3

  • Application Area:Cell biology

"Good and useful product to stain nuclei in our experiments"

Review date: 03 Nov 2017 | DRAQ7
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: Cancer Research Institute of Salamanca CSIC-USAL University



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Easy to analyze apoptosis in cells at certain phases of the cell cycle
Rating: 4.3

  • Application Area:Analyze apoptosis in cells at certain phases of the cell cycle

"The product is very easy to use for cytometry and results are reproducible. We perform simultaneous staining with Draq5 and Annexin-V on multiple myeloma cell line exposed to drugs and we follow their apoptosis at certain phases of the cell cycle."

Review date: 02 Nov 2017 | DRAQ7
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: University



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Great product, will use it again
Rating: 4.3

  • Application Area:Analyse impact of components on the fraction of compromised cells in drug delivery / drug uptake stu

"The product is easy to use, creates reliable results when comparing to other complementary techniques."

Review date: 24 Oct 2017 | DRAQ7
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: INRA



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
DRAQ7 is an easy to use viability dye that allows monitoring of cell death over time.
Rating: 4.3

  • Application Area:Cell viability

"DRAQ7 was used to measure cell death in complement-dependent-cytotoxicity experiment. Our project was to determine the ability of anti-Tn antibody to mediate death of Tn expressing in association with complement. Briefly, Tn expressing cells were incubated with anti-Tn antibody, in the presence of complement and DRAQ7 as a viability marker. Cell were incubated in Incucyte System (www.essenbioscience.com/en/products/incucyte?gclid=CObfsKOZjM8CFWMW0wodVw0JSQ) and the appearance of red fluorescence (staining of dead cells by DRAQ7) was monitored every 30 minutes. We were able to measure cell death over time by the use of DRAQ7. Fluorescence emission signal was high, and the results obtained were reproducible. Among all viability dye we have tested, it was the only one that emits strong signal after several hours of incubation. "

Review date: 19 Sep 2016 | DRAQ7
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: CHU de Quebec - Université Laval, Canada



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Superior to propidium iodide.
Rating: 5.0

  • Application Area:cell viability, FACS

"DRAQ7, a cell impermeant DNA stain, is great to assess cell viability using FACS: low autofluorescence in the infrared, ease to combine it with other fluorophores in the visible range. Much better than propidium iodide on the last account."

Review date: 28 Jun 2016 | DRAQ7
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: University of Edinburgh



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    3 out of 5
Great for imaging cell death as well as FACS
Rating: 4.0

  • Application Area:Small molecule cell death screens

"Draq7 offers a great means in which to image cell death in real time. Although the product is commonly used as a FACS marker for cell death, I have found great utility as a way to real time mark cell death using Incucyte. Con is price is slightly higher than competitor products used previously, but Draq7 is still my go to marker for cell death"

Review date: 22 Feb 2016 | DRAQ7

Manufacturer's Response

“Thank you for your review of DRAQ7. For higher throughput applications we offer a larger pack size (Code: DR710hc) reducing cost per assay by 45%”
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Houston Methodist Research



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Great product
Rating: 5.0

  • Application Area:Apoptosis analysis

"Very easy to use product for live cell analysis. Quick and efficient."

Review date: 29 Jan 2016 | DRAQ7


  • Status:

    Reviewer

  • Member since: 2011

  • Organization: Imagen biotech



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0

  • Application Area:High Content Screening

"This has enabled us to do experiments that were not otherwise possible before. Not only is it a much cleaner signal than other viability dyes, but the fact that it is non-toxic has enabled us to do time courses with the same samples. We have performed 3D spheroid experiments over a 4week period, reading plates every 72hours with zero toxicity! It therefore saves us large amounts of money that would have been spent on ending experiments at each time point using toxic dyes. Highly recommended! "

Review date: 22 Oct 2015 | DRAQ7
  • Status:

    Reviewer

  • Member since: 2015

  • Organization: HOSPITAL INFANTIL DE MÉXICO FEDERICO GÓMEZ



  • Ease of use
    5 out of 5
    After sales service
    1 out of 5
    Value for money
    3 out of 5
Rating: 3.0
"We used to stain nuclei DRAQ7 cardiac tissue of rats that developed cardiac hypertrophy embedded in paraffin. The reagent was quite stable, not gender line, besides having a very long life."

Review date: 13 Jul 2015 | DRAQ7

Manufacturer's Response

"Alejandra
We sincerely apologise if our distribution partners in Mexico are not performing to our high standards. If there is an issue with the local agents it is always possible to order direct from BioStatus for immediate delivery and our 24h response time for tech support."
  • Status:

    Reviewer

  • Member since: 2015

  • Organization: GENyO Centre, FPS



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0

  • Application Area:Viability dye in whole blood flow cytometry

"We have used DRAQ7 as a convenient viability dye in whole blood Lyse-no Wash flow cytometry protocols, included in a 8-color panel. The staining we got was excellent and no major compensation issues arrived. We will definitively keep using this dye in further projects. "

Review date: 26 May 2015 | DRAQ7
  • Status:

    Reviewer

  • Member since: 2015

  • Organization: Tottori University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0
"The greatest characteristic of DRAQ7 is Ease of Use. Short incubation time (~10 min) and excitation by near-infrared wavelength allow us to sort and eliminate dead cells in flow cytometric analysis easier. This dye also has good performance considering its low price."

Review date: 22 May 2015 | DRAQ7
  • Status:

    Reviewer

  • Member since: 2014

  • Organization: Tohoku University School of Medicine



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0

  • Application Area:Immunocytochemistry

"This product is easy-to-use, with very low photobleaching during confocal microscopic examination."

Review date: 12 Aug 2014 | DRAQ7
  • Status:

    Reviewer

  • Member since: 2014

  • Organization: The University of North Carolina at Chapel Hill



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0

  • Application Area:Research

"It is very easy to use. DRAQ is my routine far-red DNA dye."

Review date: 29 Jul 2014 | DRAQ7
  • Status:

    Reviewer

  • Member since: 2014

  • Organization: Bar-Ilan University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0

  • Application Area:Cell Health (U-251 cells)

"This product is user-friendly and does not require much effort to use. It gives good results and is clear. It can be used for a time acceptable. In addition, the company's service was superior in terms of response and availability. I am very pleased and I know I will contact the company again when I need to. "

Review date: 17 Jul 2014 | DRAQ7
  • Status:

    Reviewer

  • Member since: 2012

  • Organization: Memorial Sloan-Kettering Cancer Center



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Rating: 4.7

  • Application Area:Live cell screening

"Draq7 is a great dye for labelling cells and is very easy to use. Using this dye we have been able to do live cell screening of cells, as it is non-toxic to cells. However, overall the cost is a bit expensive for screening."

Review date: 31 Dec 2012 | DRAQ7
DRAQ7 fluoresces in the far-red – with the same spectral properties that have made DRAQ5™ a reagent of choice in HCS.

DRAQ7™ only labels membrane-compromised dead, dying and apoptotic cells and gives clear discrimination between these and healthy cells in high content cytotoxicity and viability assays and in flow cytometry.

The far-red emission, longer wavelength than TOTO-3, permits better combination with other fluorescent probes. It is spectrally compatible with the commonly used orange/red mitochondrial health probes, and UV-excited vital dyes.

DRAQ7 can be used in RNAi knock-down and long-term, dynamic viability assays to report in vitro cytotoxicity and apoptosis.

Also, DRAQ7 efficiently counterstains fixed cell and tissue preparations. It offers the same differential nucl:cyto staining for dual compartment segmentation in translocation tracking and cell morphometrics for in vitro toxicology, that has made DRAQ5™ a favourite of HCS assay developers.
 
DRAQ7 is supplied as a convenient aqueous, ready-to-use solution. The 1 ml pack size (GBP 140.00 / ca. USD 220.00) is sufficient for at least 200 flow cytometry tests, 300-600 slides and up to 10,000 1536-MTP wells.

Product Overview

DRAQ7 by Biostatus Limited product image

DRAQ7

Manufacturer Biostatus Limited  |  Available Worldwide

4.7 / 5.0 | 18 reviews