Rapid Cleanup of Oligo Therapeutics from Biological Samples
Clarity® OTX™ was designed with the fast-paced DMPK/ADME environment in mind. It is a simple, rapid, and reproducible solution that efficiently extracts oligos from biological matrices and can be easily automated to eliminate sample backlogs and meet critical deadlines. By eliminating the need for LLE (liquid-liquid extraction), providing a 96-well plate format for liquid handler compatibility, and specifically targeting synthetic oligo therapeutics chemistries, Clarity OTX delivers a 15-minute extraction procedure. • > 80% typical extraction recoveries • No LLE required • Suitable for a majority of therapeutic oligos, tissues, and fluids • Optimized for LC/MS bioanalysis
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