ChemiScreen™ CCR4 Calcium-Optimized FLIPR Cell Line

ChemiScreen™ CCR4 Calcium-Optimized FLIPR Cell Line

EMD Millipore, a division of Merck KGaA, Darmstadt, Germany

Chemicon's cloned human CCR4-expressing cell line is made in the Chem-1 host, which supports high levels of recombinant CCR4 expression on the cell surface and contains high levels of the promiscuous ...read more

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Description

 

Chemicon's cloned human CCR4-expressing cell line is made in the Chem-1 host, which supports high levels of recombinant CCR4 expression on the cell surface and contains high levels of the promiscuous G protein Ga15 to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for antagonists of interactions between CCR4 and its ligands.

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