Chemicon's cloned human 5-HT 2C -expressing cell line is made in the Chem-1 host, which supports high levels of recombinant 5-HT 2C expression on the cell surface and contains high levels of the pro...read more
Chemicon's cloned human 5-HT2C -expressing cell line is made in the Chem-1 host, which supports high levels of recombinant 5-HT2C expression on the cell surface and contains high levels of the promiscuous G protein Gα15 to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for antagonists of interactions between 5-HT2C and its ligands.
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