Caspase 3/7 Reagent Kit (100 tests)

 3.6/5.0 (1 review)

EMD Millipore, a division of Merck KGaA, Darmstadt, Germany

The Guava® Caspase 3/7 and 8 Assays employ a FLICA (Fluorescent Labeled Inhibitor of Caspases) reagent that specifically identifies active caspase 3 and 7 molecules or caspase 8 molecules. Non-cytot...read more

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Reviews

VOLKER BRIKEN


Status:


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Member since 2011

Organization:
UNIVERSITY OF MARYLAND
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RATING: 3.6

  • 5 out of 5EASE OF USE
  • 3 out of 5AFTER SALES SERVICE
  • 3 out of 5VALUE FOR MONEY




Review date: 01 Jul 2011

Caspase 3/7 Reagent Kit (100 tests)

"Works well but expensive."

Description

 

The Guava® Caspase 3/7 and 8 Assays employ a FLICA (Fluorescent Labeled Inhibitor of Caspases) reagent that specifically identifies active caspase 3 and 7 molecules or caspase 8 molecules.

Non-cytotoxic, cell permeant dyes elimiate lysis and permeabilization procedures. Each FLICA is comprised of three subunits:
A caspase-specific amino acid inhibitor containing a recognition sequence for caspase 3/7 (DEVD) or caspase 8 (LETD); a fluoromethylketone moiety (FMK) that forms a covalent linkage with the active enzyme; and a carboxyfluorescein (FAM) reporter.

The nuclear DNA stain is also included in the assay to simultaneously evaluate membrane integrity and cell viability. For use with all instruments.

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