Bio-Plex Pro RBM Kidney Toxicity Assays

Bio-Plex Pro RBM Kidney Toxicity Assays
by Bio-Rad
 4.5/5.0 (2 reviews)

The Bio-Plex Pro RBM kidney toxicity assays, developed in partnership with Myriad RBM, comprise a highly relevant set of biomarkers for early detection and characterization of kidney toxicity/injury. Myriad RBM’s close collaboration with the Predictive Safety Testing Consortium (PSTC), FDA, and European Medicines Evaluation Agency (EMEA) was instrumental in the selection of markers found in these ...read more

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Reviews

AVERAGE RATING: 4.5

2 scientists have reviewed this product

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  • 5 out of 5EASE OF USE
  • 5 out of 5AFTER SALES SERVICE
  • 5 out of 5VALUE FOR MONEY

Subham Das


Status:


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Member since 2014

Organization:
Kalinga Institute of Medical Sciences
Read more »
RATING: 5.0

  • 5 out of 5EASE OF USE
  • 5 out of 5AFTER SALES SERVICE
  • 5 out of 5VALUE FOR MONEY




Review date: 27 Aug 2014

Application Area: clinical trial
Bio-Plex Pro RBM Kidney Toxicity Assays

"A very sophisticated product, easy to use and good value for money. Plus you get the renowned after-sales service of Bio-Rad."

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Christopher Bianca


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Member since 2013

Organization:
JRFAmerica
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RATING: 4.0

  • 4 out of 5EASE OF USE
  • 4 out of 5AFTER SALES SERVICE
  • 4 out of 5VALUE FOR MONEY




Review date: 11 Jul 2014

Application Area: Enzyme Toxic Effect Metabolism Chemistry
Bio-Plex Pro RBM Kidney Toxicity Assays

"As a teaching tool it is very good and useful. It is an easy kit to use, its self explanatory and well developed. It is very useful as a marker to enzymatic effects from certain compounds. I've recommended as a very useful laboratory tool."

Description

 

The Bio-Plex Pro RBM kidney toxicity assays, developed in partnership with Myriad RBM, comprise a highly relevant set of biomarkers for early detection and characterization of kidney toxicity/injury. Myriad RBM’s close collaboration with the Predictive Safety Testing Consortium (PSTC), FDA, and European Medicines Evaluation Agency (EMEA) was instrumental in the selection of markers found in these panels.

The assays are built on magnetic beads to enable robust quantification of multiple proteins in human urine samples, providing valuable information throughout drug development — from lead optimization to preclinical and clinical protocol decision making. Assays are offered as premixed all-in-one kits for research involving:

• Drug-induced kidney toxicity
• Diabetes
• High blood pressure
• Glomerulonephritis
• Polycystic kidney disease
• Chronic infection
• SLE (lupus) and other autoimmune disorders

Bio-Plex Pro RBM human kidney toxicity assays are available as two panels:

Panel 1
• Calbindin
• Clusterin
• GST-π
• IL-18
• KIM-1
• MCP-1

Panel 2
• Albumin
• B2M
• Cystatin C
• NGAL
• Osteopontin
• TFF3

Based on 6.5 µm magnetic beads, these assay panels are compatible with both vacuum and magnetic wash stations. Magnetic washing simplifies plate processing, provides increased throughput, and results in decreased variability and increased reproducibility.

Key Features
• Optimized for high precision and lot-to-lot reproducibility of sample measurements
• Magnetic beads for simplified plate processing
• 2-level quality controls with lot-specific ranges
• Assay quick guide to get you started right away
• High-quality design ensures robust and reproducible measurement of nephrotoxicity biomarkers in human, rat, and canine urine samples

Premixed all-in-one kits

Instrument Compatibility
• Bio-Plex® MAGPIX™ multiplex reader
• Bio-Plex® 200 systems
• Bio-Plex 3D suspension array system
• Bio-Plex Pro wash stations

Product Overview

Bio-Plex Pro RBM Kidney Toxicity Assays by Bio-Rad
Bio-Plex Pro RBM Kidney Toxicity Assays




  • 5out of 5EASE OF USE
  • 5 out of 5AFTER SALES SERVICE
  • 5 out of 5VALUE FOR MONEY





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