ACQUITY UPLC System

Manufacturer Waters
4.0
/
5.0
  |  100 reviews



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Average Rating: 4.0
100 Scientists have reviewed this product

4 out of 5
Ease of use
4 out of 5
After sales service
4 out of 5
Value for money


Reproduce great results and chromatograms
Rating: 4.7

  • Application Area: Analyzing metabolites in tissue and plasma, and plant metabolites.

"System is easy to use and reproduce reliable data for analysis of samples and natural product chemical finger printing."

Review date: 29 Nov 2016 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Noramco



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
The Classic Acquity is my favorite instrument!
Rating: 4.7

  • Application Area:Small Molecule Method Development

"Love the Classic Acquity! This is a great instrument. Dependable and runs like a Mercedes!"

Review date: 04 Nov 2016 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Alcon Research LTD



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Shortened the run time by 50%. Very reliable instrument.
Rating: 5.0

  • Application Area:Polymer, chemical assay

"Great instrument, easy to use, friendly service man, get the results within a click"

Review date: 23 May 2016 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Albany College of Pharmacy and Health Sciences



  • Ease of use
    4 out of 5
    After sales service
    2 out of 5
    Value for money
    4 out of 5
Works well but could be better.
Rating: 3.3

  • Application Area:Analyzing various samples

"Works well as far as I know. I am currently a student so I don't purchase the equipment."

Review date: 31 Mar 2016 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Syngene International Limited



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
I am strongly recommending to buy acquity UPLC
Rating: 4.0

  • Application Area:Analysis of Pharmaceutical products

"Easy to use, can get precise results, baseline noise might arise for some time "

Review date: 30 Mar 2016 | ACQUITY UPLC System


  • Status:

    Reviewer

  • Member since: 2015

  • Organization: InVision Biomedical Group



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Absolutely a must have for any discovery laboratory doing UPLC work
Rating: 5.0

  • Application Area:Bioanalytical Impurity Analysis

"Robust, highly reproducible, great after purchase care, lots of options in terms of tubing/line compatibility, injection settings, extensions, etc. Lots of detectors available."

Review date: 29 Feb 2016 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: Virginia Commonwealth University



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
A powerful UPLC system which is robust.
Rating: 4.3

  • Application Area:Small molecule analysis and glycosaminoglycan analysis

"The Waters Acquity UPLC system is a robust UPLC machine which we use regularly in our lab. The system has been down less than 1% of the time. I do recommend getting a preventive maintenance plan with the machine though to keep it running in top condition. The Waters Tech support is great to work with and quick to respond."

Review date: 19 Nov 2015 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2015

  • Organization: NBTY Inc



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
Rating: 4.3

  • Application Area:Release Finished Goods

"Easy to use with excellent accuracy and readable results"

Review date: 09 Nov 2015 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2010

  • Organization: medimmune



  • Ease of use
    3 out of 5
    After sales service
    3 out of 5
    Value for money
    3 out of 5
Rating: 3.0

  • Application Area:stability and characterization

"System purchased was needed to analysis stability of peptide samples. although method development was reasonably straight forward, getting the sensitivity was an issue. I would recommend as it is one of the leading systems for this type of work "

Review date: 06 Nov 2015 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2015

  • Organization: Scool of Pharmacy-Unversity of Maryland.edu, Baltimore



  • Ease of use
    3 out of 5
    After sales service
    5 out of 5
    Value for money
    3 out of 5
Rating: 3.7

  • Application Area:Bioanalysis

"UPLC and UPLC columns are not very well suited for bioanalysis and handling of "dirty samples" the lifetime of the columns is too short."

Review date: 06 Nov 2015 | ACQUITY UPLC System
  • Status:

    Advanced Reviewer

  • Member since: 2006

  • Organization: CSIR Biosciences



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Rating: 4.7

  • Application Area:Metabolomics

"The UPLC is robust, easy to use and produced excellent results in long metabolomic experiments lasting up to 8 days. The quality of the data resulted in more than 55 publications to date. The support service is excellent and application support outstanding. I can recommend this UPLC system to any researcher requiring quality analytical data. "

Review date: 02 Nov 2015 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2006

  • Organization: GSK



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Rating: 4.0

  • Application Area:DMPK

"Waters Acquity Systems has made a significant difference to the Quality of Data we generate and also enhanced our operating efficiency! "

Review date: 02 Nov 2015 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: Dr. Reddys



  • Ease of use
    2 out of 5
    After sales service
    2 out of 5
    Value for money
    2 out of 5
Rating: 2.0

  • Application Area:Pharmaceutical analysis

"Waters Acquity UPLC system is one of the inventions in analytical chemistry. This system can be used as HPLC as well as UPLC but due to complexity of design it always shows continuous malfunctions and major break down issues. Rectification of problems is costly and time affect productivity. Now need of pharmaceutical industry has shifted to sensitivity and there is still enough scope for versatile detector which capable to quantify accurately UV active and non-active compounds in single analysis cost effectively."

Review date: 02 Nov 2015 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2010

  • Organization: US FDA



  • Ease of use
    5 out of 5
    After sales service
    3 out of 5
    Value for money
    3 out of 5
Rating: 3.7

  • Application Area:Cosmetics

"The Water UPLC System is great and effective with high quality"

Review date: 02 Nov 2015 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2014

  • Organization: CienVar Laboratories



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0

  • Application Area:Pharmaceutical

"We use the UPLC system in our company and we have been able to analyze our samples in a more rapid and reproducible manner. I think it is a technique that helps pharmaceutical laboratories to quickly bring to market their products. "

Review date: 22 Oct 2015 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2015

  • Organization: Lupin Limited



  • Ease of use
    3 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
Rating: 4.0

  • Application Area:Biosimilars

"Everyone thinks Acquity UPLC is more user friendly. But, Empower software is very complicated and it is not user friendly. UPLC has not showed better resolution than an HPLC. Methods can be faster in UPLC. But, Resolution is better in UHPLC than UPLC. So many issues with the hardware of UPLC. It is very difficult to find the trouble in the system "

Review date: 14 Sep 2015 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2014

  • Organization: Distell



  • Ease of use
    3 out of 5
    After sales service
    1 out of 5
    Value for money
    1 out of 5
Rating: 1.7

  • Application Area:Quantification of phenolic compounds in cider

"The system is connected to a triple-quadrupole MS. It is leaching metal ions. So, I'm seeing a lot of ion suppression. Our solvents are clean."

Review date: 28 Jul 2015 | ACQUITY UPLC System
  • Status:

    Expert Reviewer

  • Member since: 2013

  • Organization: BCSIR



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0
"This ACQUITY UPLC System supports us for drug discovery including small molecules and also testing for safety in food materials. Now we can get more information in a single, short run than usual HPLC. So it saved money, labor and supports a lots for our research. "

Review date: 20 Mar 2015 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: Bristol Myers Squibb



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Rating: 4.0
"So pleased to have UHPLC in our lab, it saves much time in terms of development."

Review date: 17 Dec 2014 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: Colgate Palmolive



  • Ease of use
    5 out of 5
    After sales service
    3 out of 5
    Value for money
    5 out of 5
Rating: 4.3

  • Application Area:Pharmaceuticals

"This high-end sophisticated product is best suited for existing HPLC methods and also for new methods in terms of speed without compromising resolution and sensitivity. A very good tool for impurity profiling and method development. In today's fast world, where high productivity in terms of sample analysis is expected in less time this product is an apt answer. Not only it is faster but you can combine it with any detector either of Waters makes or of a different manufacturer which makes its applications even more wider which is a good value for money. And with Waters own "Empower" software it becomes easier to operate even for a novice person. A must have for each Analytical laboratory. "

Review date: 05 Nov 2014 | ACQUITY UPLC System
  • Status:

    Advanced Reviewer

  • Member since: 2013

  • Organization: Ei, LLC



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Rating: 4.0

  • Application Area:Chromatographic Analysis

"This is a highly sophisticated instrument with a wide range of capabilities and exhibits reproducible and robust chromatography."

Review date: 16 Jun 2014 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2014

  • Organization: Momentive Specialty Chemicals



  • Ease of use
    3 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Rating: 4.0

  • Application Area:Separation And Molecular Weight

"The instrument works fine. However its Empower software is difficult to use unless you are very familiar with it and use it every day. For molecular weight measurement, the software cannot give numbers based on individual peaks and whole chromatograph at the same time. But the after sales service is excellent. "

Review date: 13 Mar 2014 | ACQUITY UPLC System
  • Status:

    Expert Reviewer

  • Member since: 2013

  • Organization: Pharmazentrum, University Of Basel



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0

  • Application Area:Bioanalysis Of Natural Products

"Excellent system, Waters was the 1st on the market of UPLC so their systems are easy to use, very robust and have extremely less carry over issues with their needle in peek. The dead volume is extremely small."

Review date: 23 Dec 2013 | ACQUITY UPLC System
  • Status:

    Expert Reviewer

  • Member since: 2013

  • Organization: JRFAmerica



  • Ease of use
    3 out of 5
    After sales service
    3 out of 5
    Value for money
    3 out of 5
Rating: 3.0

  • Application Area:Residue Chemistry And E-Fate Metabolism Chemistry

"The system is functional and it meets its needs for large molecule analysis, but for residue studies it has its problems with carry over. Also when control by other software besides waters there are many communication issues. It is a useful tool and it is easy to work with, but I would recommend not using it for residue chemistry, unless someone has validated the method and you know the problems from the beginning. However it is very useful connected to a ToF Mass Spec for Proteomics I have seen great results for peptide ID it tends to handle buffers better than other systems. "

Review date: 25 Nov 2013 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: Evira



  • Ease of use
    4 out of 5
    After sales service
    1 out of 5
    Value for money
    3 out of 5
Rating: 2.7

  • Application Area:Amino acid analysis with AcqTag application

"The sample derivatization method is easy to implement. The separation of amino acids with UPLC worked immediately without any method tuning or problems. The cleaning procedure of the UPLC after other analyses is quite demanding (takes one day), so maybe not be very applicable if the instrument is used also for other analyses or at least demands good planning of the instrument use. The eluents are quite expensive and according to label suitable for use for one month after opening. Thus method is quite expensive if analyses are done rarely."

Review date: 11 Sep 2013 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: Gedeon Richter Plc.



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Rating: 4.3

  • Application Area:Analytical validation, QC

"Very good instrument, easy to use. I only used it one year ago and there were no problems with it. The technical support in Hungary is very good and the team is helpful."

Review date: 12 Aug 2013 | ACQUITY UPLC System
  • Status:

    Expert Reviewer

  • Member since: 2013

  • Organization: Pharmazentrum, University Of Basel



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0

  • Application Area:bioanalysis

"Very good system especially low carry over system with the peak needle. It is extremely robust, you can fix it by yourself easily without problems."

Review date: 08 Aug 2013 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: AMC



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Rating: 4.3

  • Application Area:Hormone diagnostics

"The Waters Acquity UPLC system has been in our lab now for about 4 years and we are very satisfied with it. It is nice with very few problems. Firstly we coupled it to a Quattro Premier Mass spec, but as soon as we bought a Xevo TQS we coupled it to that one."

Review date: 08 Aug 2013 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: Vrije Universiteit Brussel



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    3 out of 5
Rating: 4.0

  • Application Area:oncologic

"It is a good technique, easy and friendly to use. The software is intuitive in MS and UV and gives a high performance of resolution and a good speed. The instrument tolerates high pressure and high flow rate. I really recommend this apparatus."

Review date: 08 Aug 2013 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: Hospira



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 4.7

  • Application Area:pharmaceutical

"Great system and incredible support. The follow up and support is some of the best in the industry and the robustness of the system has been great in our applications so far."

Review date: 19 Jul 2013 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: Bristol Myers Squibb



  • Ease of use
    3 out of 5
    After sales service
    3 out of 5
    Value for money
    4 out of 5
Rating: 3.3

  • Application Area:Pharmaceutical

"Very robust instruments. Great savings in time and money. Support is good. Multiple applications in the pharmaceutical industry."

Review date: 26 Jun 2013 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: Teva Pharmaceuticals USA



  • Ease of use
    4 out of 5
    After sales service
    3 out of 5
    Value for money
    3 out of 5
Rating: 3.3

  • Application Area:Small molecule analysis

"Easy to use and rugged for method development. The system also requires minimum maintenance. However, back pressure often results in loss of target peaks."

Review date: 26 Jun 2013 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: University of Virginia



  • Ease of use
    4 out of 5
    After sales service
    3 out of 5
    Value for money
    4 out of 5
Rating: 3.7

  • Application Area:pharmaceutical

"The Acquity UPLC Waters system is a great product that is relatively simple to use. The trouble shooting was not too hard and the services did a great job helping with the problem."

Review date: 03 Jun 2013 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: Dr Reddys Laboratories Ltd



  • Ease of use
    3 out of 5
    After sales service
    3 out of 5
    Value for money
    3 out of 5
Rating: 3.0

  • Application Area:Pharmaceutical

"Very good for high accurate analysis. Also it is proven for repeatability and reliability of the results. "

Review date: 03 Jun 2013 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: Merck & Co., Inc



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Rating: 4.0

  • Application Area:bioanalysis

"I would recommend this product as it is easy to setup and use. However, there are communication issues when you control it through non-Waters software. Waters is also very helpful for questions and additional training."

Review date: 03 Jun 2013 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: Georgia State University, Chemistry



  • Ease of use
    3 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Rating: 3.7
"Highly rated for both rugged and state of the art work, this is a great HPLC will be a revolution in science."

Review date: 03 Jun 2013 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: Dow Electronic Materials



  • Ease of use
    4 out of 5
    After sales service
    2 out of 5
    Value for money
    4 out of 5
Rating: 3.3

  • Application Area:QC

"Allows for fast analysis of samples, however we are currently having repeatability issues. Installation is quick and easy. When working properly it will allow for quick method development and quicker sample turnaround times with little eluent use."

Review date: 03 Jun 2013 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: Sciegen pharmaceuticals, inc



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 4.7

  • Application Area:pharmaceuticals

"A very good product to use in fast phase environment. Cost effective and a solvent saver. "

Review date: 03 Jun 2013 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: Bristol Myers Squibb



  • Ease of use
    3 out of 5
    After sales service
    3 out of 5
    Value for money
    3 out of 5
Rating: 3.0

  • Application Area:small molecules

"This is a very easy to use system. It works great and is fast. Sometimes it might have problems but it is easy to fix. It is definitely valuable for the money."

Review date: 03 Jun 2013 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: Evonik Oil Additives USA, Inc



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
Rating: 4.7

  • Application Area:analysis of monomer inhibitors

"The instrument is useful because it shortens analysis time leading to higher productivity. It also uses smaller sample sizes and uses less solvent so it is more economical and environmentally friendly as well."

Review date: 29 May 2013 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: Noramco



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0

  • Application Area:Pharmaceuticals

"Wonderful product. Easy to use with cutting edge technology. Great value for money and has revolutionized the industry."

Review date: 28 May 2013 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2006

  • Organization: Genomics Institute of the Novartis Research Foundation



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0

  • Application Area:Pharmaceutical Research

"The Waters Acquity UPLC system is the best UHPLC on the market. Their pump technology is unrivalled in the industry. Our LC run times have gone down to 1/4 of original and we save money on solvents and consumables."

Review date: 28 May 2013 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: Regeneron



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Rating: 4.3
"The Waters Acquity UPLC system is great because it offers excellent sensitivity and resolution.  It is a very reliable instrument.  It is my UPLC of choice and I would absolutely recommend it to a colleague."

Review date: 28 May 2013 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2010

  • Organization: University of Texas at Arlington



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0

  • Application Area:pharmaceutical

"Easy to use and very quick. It has applications for environment, biological, and pharmaceutical and so on. Peak shapes are sharp and time saving."

Review date: 28 May 2013 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: Merck



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
Rating: 4.3

  • Application Area:bioanalytical, proteins

"The waters Acquity UPLC is heavily utilized daily in my laboratory for bioanalytical assays of proteins and small molecule residuals. The resolution and sensitivity that can be achieved is worth the cost. The Empower software is easy to use after a slightly difficult learning period. At first the software seemed difficult (relative to Chemstation) but now that I am using it often I prefer Empower. One great benefit is the Acquity console that controls instrument and column and has easy access to column information and literature. This instrument is critical for our success."

Review date: 28 May 2013 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: GlaxoSmithKline



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0

  • Application Area:pharmaceuticals

"Fantastic system for routine pharma analysis.  Used for over 7 years, and continue to use for many more."

Review date: 28 May 2013 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: US Pharmacopeial Convention



  • Ease of use
    4 out of 5
    After sales service
    3 out of 5
    Value for money
    4 out of 5
Rating: 3.7

  • Application Area:Separations

"Wonderful system.  Worked equally well for small molecules as well as proteins.  Reliable and easy to validate for use in a QC environment.  Handled a large volume of samples routinely and efficiently."

Review date: 28 May 2013 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: Johnson&Johnson (Noramco)



  • Ease of use
    3 out of 5
    After sales service
    3 out of 5
    Value for money
    3 out of 5
Rating: 3.0

  • Application Area:API

"The UPLC has been a great addition to the lab, however, it does require a lot of service. We have had to call in the vendor on several occasions to fix the check valve. When it is working properly, the instrument has been beneficial to the lab."

Review date: 28 May 2013 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: Abbott



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Rating: 4.0

  • Application Area:open access LC/MS

"This system has been robust in our walk-up LC/MS environment. The unit sees heavy use with little downtime. I would definitely recommend the Acquity Classic for anyone considering walk-up LC/MS applications."

Review date: 28 May 2013 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: Merck



  • Ease of use
    4 out of 5
    After sales service
    3 out of 5
    Value for money
    5 out of 5
Rating: 4.0

  • Application Area:biopharmaceuticals

"In my lab, we use the Acquity UPLC H -Class as its use in the biopharmaceutics makes it easy to run in high salt conditions. The flow path is completely steel free making it more robust against salt build up. To quantitate data, Empower makes it very easy to run many samples and process data."

Review date: 28 May 2013 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2012

  • Organization: Apotex Inc.



  • Ease of use
    4 out of 5
    After sales service
    3 out of 5
    Value for money
    5 out of 5
Rating: 4.0

  • Application Area:Pharmaceutical Testing

"UPLC saves time by reducing the run time. It’s very efficient and uses less solvent with a faster run time. UPLC is able to produce better chromatography by providing sharp peaks and a complete resolution between many analytes that are being separated from the sample substance in question."

Review date: 28 May 2013 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: Apotex



  • Ease of use
    4 out of 5
    After sales service
    3 out of 5
    Value for money
    4 out of 5
Rating: 3.7
"It is most efficient with a fast run time to analyze the sample. The column is very short. The peak is very sharp and narrow, the resolution is achievable within the three minutes run time."

Review date: 28 May 2013 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: GlaxoSmithKline



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Rating: 4.0

  • Application Area:pharmacueticals

"The instrument is easy to use, and easy to track column history with the chip. However, the system column installation is not quite user friendly. I like the fusion system that has been developed to support method development using UPLC. However, the software seems only include statistic function, but not the chromatographic basic theory. In general, I like the system. "

Review date: 23 May 2013 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2012

  • Organization: Dow AgroSciences LLC.



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0

  • Application Area:Chemistry characterization

"Waters' UPLC and LCMS systems with the Masslynx platform offer the most reliable and versatile systems in the world. In addition to their ruggedness, Waters as a company offers outstanding after the sale service. Engineers are well trained in all aspects of their instruments and are readily available to help. In my experience, first response takes no longer than 24 hrs and a solution is reached between 24 to 72 hrs. Their telephone support is remarkable, you no longer have to leave a message and someone has to get back to you to solve your issue. The person answering the call is the person who will help and solve your issue. They also have the capability to log into your computer system to fix any problems directly from Milford. I have experience with other vendors in the same area as we also have competitors LC/MS systems and compared side to side, Waters by far tops them all."

Review date: 13 Nov 2012 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2012

  • Organization: Abbott Laboratories



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    3 out of 5
Rating: 3.7

  • Application Area:Bioanalytical

"Instrument is easy to use (similar to Waters HPLC systems). It uses less sample as well as mobile phase. More pumps so multiple mobile phase can be used for selectivity."

Review date: 01 May 2012 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2010

  • Organization: Covidien



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Rating: 4.3

  • Application Area:Pharmaceuticals

"The UPLC system is very easy to use and is one of the biggest time savers on our lab. However communication issues with the autosampler are problematic."

Review date: 26 Mar 2012 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2010

  • Organization: Pfizer



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
Rating: 4.7

  • Application Area:Analytical Chemistry

"Fast and reliable separations on final purified compounds. Excellent software- MassLynx4.1, with intelli-start technology. High pressure capabilities coupled with great resolution."

Review date: 23 Mar 2012 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2010

  • Organization: Western Slope Laboratory, LLC



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Rating: 4.3

  • Application Area:Toxicology testing

"Great separations, fast run times, faster infusions with Intellistart."

Review date: 23 Mar 2012 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2010

  • Organization: PharMEDium Services, LLC



  • Ease of use
    3 out of 5
    After sales service
    3 out of 5
    Value for money
    3 out of 5
Rating: 3.0
"A robust instrument, however there are no leak detectors which can be problematic in the column department. Using the Empower software for the instrument can be challenging. Technical support for the instrument has been great. Service engineers respond within 12-24 hours."

Review date: 23 Mar 2012 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2010

  • Organization: ILIS



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Rating: 4.7

  • Application Area:Pharmaceutical Analysis

"Good equipment with very good separation. Very good technical support for technical questions. Good columns for UPLC and UPLC separations of natural products."

Review date: 23 Mar 2012 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2010

  • Organization: Bristol-Myers Squibb



  • Ease of use
    2 out of 5
    After sales service
    5 out of 5
    Value for money
    3 out of 5
Rating: 3.3

  • Application Area:Pharmaceuticals

"Great high pressure system for impurites/degradants detection. It is expensive but the customer service is good."

Review date: 22 Mar 2012 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2010

  • Organization: Amneal Pharmaceuticals



  • Ease of use
    1 out of 5
    After sales service
    1 out of 5
    Value for money
    2 out of 5
Rating: 1.3

  • Application Area:Pharma Analysis

"Very sensitive, not rugged, lots of trouble shooting. Poor pump and no binary pump."

Review date: 21 Mar 2012 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2010

  • Organization: Tennessee Technological University



  • Ease of use
    3 out of 5
    After sales service
    3 out of 5
    Value for money
    3 out of 5
Rating: 3.0

  • Application Area:Pharmaceutical Analysis

"Operates at high pressures, up to 15,000 psi. Good resolution with a wide range of linear velocities. It has a rapid analysis time and the high resolution results in narrow peak widths and an increased signal/noise ratio."

Review date: 21 Mar 2012 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2010

  • Organization: NC BioNetwork



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0

  • Application Area:Analytical chemistry training

"Equipment is great for taking existing HPLC methods and converting them to faster more resolved UPLC methods. The system compliments nicely to UPLC H-Class in ease of use and affordability. Customer service is always willing to help when a problem arises. Service is prompt and excellent."

Review date: 21 Mar 2012 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2010

  • Organization: Tecnoquimicas S.A.



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Rating: 4.7

  • Application Area:Assay Analysis and Development

"Versatile and easy to use, even for new technicians. Excellent training program. After sales service has been quick, efficient and helpful."

Review date: 20 Mar 2012 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2012

  • Organization: Merck



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0

  • Application Area:Pharmaceutical drug development assays

"Using the Acquity we are able to reduce analysis time and solvent usage/waste (and preparing less mobile phase takes less labtime as well). The Waters support is fantastic; their engineers 'know their stuff' and work to constantly improve the product. The resolution tends to be better with the UPLC (vs. HPLC), and I've found the instruments to be as robust as typical HPLCs. The columns will clog more easily, however I've found that a pre-column filter saves the column if there are large particulates in the sample."

Review date: 27 Feb 2012 | ACQUITY UPLC System
  • Status:

    Advanced Reviewer

  • Member since: 2011

  • Organization: Almirall



  • Ease of use
    5 out of 5
    After sales service
    3 out of 5
    Value for money
    4 out of 5
Rating: 4.0
"Easy to use, has excellent software."

Review date: 31 Aug 2011 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: CQM, UMA



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Rating: 4.0
"In my opinion, the price should be more competitive."

Review date: 18 Aug 2011 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: TEVA Pharmaceutical Works Plc



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 4.7
"Robust, efficient and fast."

Review date: 18 Aug 2011 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: Teva Pharmaceutical Works



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Rating: 4.3
"Fast and reliable instrument."

Review date: 18 Aug 2011 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: Egis Plc



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Rating: 4.3
"Very good equipment."

Review date: 15 Aug 2011 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: Heineken



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0
"The best in UPLC."

Review date: 03 Aug 2011 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: King Saud University



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Rating: 4.3
"The sensitive and very fast separation was achieved with this instrument."

Review date: 03 Aug 2011 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: King Saud University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Rating: 4.7
"Fast, sensitive and selective."

Review date: 03 Aug 2011 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2011



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    3 out of 5
Rating: 4.0
"System very convenient and adapted for our use in compound management."

Review date: 22 Jun 2011 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: Tempur Pedic Technologies



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0
"great resolution and speed."

Review date: 14 Jun 2011 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: University of Alberta



  • Ease of use
    3 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Rating: 3.7
"Really works for shortening the times on LC separations. Really sturdy and resistant for education."

Review date: 14 Jun 2011 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: GlaxoSmithKline



  • Ease of use
    3 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
Rating: 4.0
"Went from 60 minute runs to 3 minute runs. Saves a lot of time."

Review date: 08 Jun 2011 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2010

  • Organization: NSWC



  • Ease of use
    4 out of 5
    After sales service
    3 out of 5
    Value for money
    3 out of 5
Rating: 3.3
"My problem is at the intersection of our IT and their computer control."

Review date: 06 Jun 2011 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2010

  • Organization: Arista Laboratories



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0
"Waters has helped us not only with method transfer, but also to revisit existing methods in order to improve them."

Review date: 31 May 2011 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: Eli Lilly and Company



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    3 out of 5
Rating: 4.0
"Problems with software."

Review date: 25 May 2011 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: UNC-CH



  • Ease of use
    3 out of 5
    After sales service
    4 out of 5
    Value for money
    3 out of 5
Rating: 3.3
"The fittings seem to break quite frequently but the service team is quick to help."

Review date: 25 May 2011 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: Mead Johnson Nutrition



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Rating: 4.7
"Great instrument and easy to use. The sales and application specialists have been great since purchase."

Review date: 25 May 2011 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: Teva Canada



  • Ease of use
    3 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 4.3

Review date: 04 May 2011 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: Covidien



  • Ease of use
    3 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Rating: 4.0
"The instrument is very easy to use. The Empower software itself is still fairly glitchy with regards to its connectivity with Citrix servers."

Review date: 20 Apr 2011 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: Array BioPharma



  • Ease of use
    3 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Rating: 4.0
"We use the 1st generation/high pressure LC from Waters. There were initial problems with the 1st generation product but it works well. We have had lots of help from Waters tech service."

Review date: 19 Apr 2011 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: Ramguz S.A.



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Rating: 4.7
"Excellent system, saves money with solvents."

Review date: 08 Apr 2011 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: North Carolina State University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Rating: 4.7
"Innovative technology!"

Review date: 07 Mar 2011 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2007

  • Organization: Bristol-Myers Squibb



  • Ease of use
    3 out of 5
    After sales service
    3 out of 5
    Value for money
    4 out of 5
Rating: 3.3
"Good robust system. Occasional autosample issues. Intergration issues with other instrument. Nickel coating contamination in mobile phase."

Review date: 04 Feb 2011 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2010

  • Organization: Xcelience



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Rating: 4.0

Review date: 16 Apr 2010 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2009

  • Organization: Abbott



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0
"A laboratory workhorse."

Review date: 01 Jul 2009 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2009

  • Organization: PFIZER



  • Ease of use
    3 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Rating: 3.7
"This product has improved column efficiency and separation."

Review date: 16 Apr 2009 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2009

  • Organization: BOEHRINGER INGELHEIM (CANADA) LTD.



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Rating: 4.3
"A very innovative system with great customer support."

Review date: 16 Apr 2009 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2009

  • Organization: PFIZER



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Rating: 4.3
"I have had some troubles with reliability and Waters have tried to be helpful but they are not very quick. Nonetheless, the systems are great when they work."

Review date: 15 Apr 2009 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2009

  • Organization: COVANCE LABORATORIES, INC.



  • Ease of use
    1 out of 5
    After sales service
    1 out of 5
    Value for money
    1 out of 5
Rating: 1.0

Review date: 15 Apr 2009 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2009

  • Organization: COVANCE



  • Ease of use
    2 out of 5
    After sales service
    3 out of 5
    Value for money
    2 out of 5
Rating: 2.3
"Application is easy but its use is difficult."

Review date: 15 Apr 2009 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2007

  • Organization: Biogen idec.



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Rating: 4.3

Review date: 12 Sep 2008 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2008

  • Organization: Xenon Pharmaceuticals



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Rating: 4.0

Review date: 22 Feb 2008 | ACQUITY UPLC System
  • Status:

    Reviewer

  • Member since: 2007

  • Organization: Univ Miami



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 4.7

Review date: 11 Jan 2008 | ACQUITY UPLC System

Waters ACQUITY UPLC - Dramatic Improvements in Speed, Sensitivity and Resolution

Whether you work in methods development or quality assurance, in drug discovery and development or testing for safety in food supplies, you seek a productivity edge. With the ACQUITY UPLC® System, now you can get more information in a single, short run than you've ever seen with HPLC.

Waters ACQUITY UPLC System
UltraPerformance LC® (UPLC®) technology starts with unique 1.7 μm small-particle chemistries. Chromatographers no longer need to choose between speed and resolution–with UPLC you get both.

Instrument Designed for Chemistry; Chemistry Designed for the Instrument
The ACQUITY UPLC System has been holistically designed to match the performance needs of our innovative column chemistries with robust hardware, easy-to-use software and specialized support services.

  • Small, pressure-tolerant particles
  • High-pressure fluidic modules
  • Minimized system volume
  • Negligible carryover
  • Reduced cycle times
  • Fast response detectors
  • Integrated system software and diagnostics

With UPLC you have the ability to work more efficiently with higher speed, sensitivity and resolution at a much wider range of linear velocities, flow rates and backpressures to obtain superior results.

The Waters ACQUITY UPLC System's high-pressure fluidics optimizes flow rates to make the most of small particle technology. The ACQUITY UPLC System's sample-handling design is designed to ensure exceptionally low carryover and reduced cycle time. And when interfaced with the Sample Organizer, it increases unattended sample capacity by ten times.

High-speed detectors, both optical and mass, contribute to increased sensitivity and help manage the heightened speed and resolution requirements of UPLC.

ACQUITY UPLC Systems are easily controlled, diagnosed, and monitored via a graphical system console interface. The console offers:

  • Quick and easy access to critical instrument parameters
  • Simple system start-up, elegant system status monitoring and predictive performance indicators to ensure maximum productivity
  • Data management capabilities that are supported by both MassLynx™ and Empower™ software
  • The ACQUITY UPLC System is also supported by Intelligent Device Management technology with our Connections® INSIGHTservice, providing instrument diagnostics.