UPC²: Expanding the boundaries of LC and GC separations

UltraPerformance Convergence Chromatography™ (UPC²™) is a new category of separations science that makes the complex analysis...routine. This new technology marries the unrealized potential of SFC with Waters proven UPLC® technology and expertise in the management of fluids, temperature, and pressure. By varying mobile phase strength, pressure, temperature, and stationary phase with UPC², one can separate, detect and quantify structural analogs, isomers, enantiomeric and diasteriomeric mixtures – all compounds or samples that challenge today’s laboratories. Because CO₂ is the primary mobile phase for UPC², the technique greatly reduces the use of toxic solvents.

ACQUITY UPC² System: Discover what's been missing from your analytical toolbox

With the ACQUITY UPC² System, scientists can now separate, analyze, and understand compounds that have challenged all other LC and GC technologies including:
•   Hydrophobic and chiral compounds
•   Lipids
•   Thermally-labile samples
•   Polymers

It's also the perfect complement to MS due to its low solvent load and high resolution, narrow peaks and fast separations.

System features:
•   Compressed carbon dioxide (CO₂), the primary mobile phase, is less costly and less toxic than liquid mobile phases or carrier gases.
•   Variable volume injection delivers 0.5 µL to 10 µL as well as the ability to match column and injection volume with minimal sample loss and need to change loops.
•   Higher throughput and productivity allows you to analyze more samples per day with faster re-equilibration of columns and shorter cycle times, increasing laboratory productivity.
•   Co-solvent and column switching provides flexibility in method development for faster solvent screening and faster column screening.