Products & ReviewSpectroscopy

ACQUITY QDa Mass Detector

WatersAvailable: Worldwide

The ACQUITY QDa® Mass Detector gives you certainty above all else. You can minimize the risk of unexpected coelutions or components and confirms trace components with the analytical confidence of mass detection. The ACQUITY QDa® Detector is a mass detector built around the needs of analytical scientists for chromatographic analysis. Robust, reliable and requiring no sample adjustments, it just integrates with your current L…

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Reviews

Average Rating 4.6

|20Scientists have reviewed this product

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Overall good MSD for compound identification, quantification and purification

 

Average Rating 5.0

Application Area:

Identification

Mass spectrometry (MS) plays a crucial role in the pharmaceutical industry, offering powerful capabilities for the identification, characterization, and quantification of compounds. Waters QDa is a good mass spectrometer designed for pharmaceutical applications that delivers unmatched sensitivity, precision, and accuracy, also ensures the highest standards in drug development and quality control.

Review Date: 7 Dec 2024 | Waters

Great results from a tiny mass detector

 

Average Rating 5.0

Application Area:

Peptides

Excellent instrument. By using this, we increased the capacity of our lab. In addition, due to its user friendly software, undergraduate students love it. We are running daily several samples, usually products of our peptide synthesis lab, but not only. We have the mass detector in line with the PDA so we can have orthogonal detection. You can find in the web our latest publications. Now we are planning to advance our research in detection of small molecules or metabolites in human liquids... blood, serum, urine, etc...

Review Date: 26 Jul 2022 | Waters

Very user friendly results comparable with much more expensive single quad MS modules

 

Average Rating 5.0

Application Area:

Pharmaceuticals

Very easy to learn how to use, works exactly as PDA. Uses empower software.

Review Date: 17 Jul 2022 | Waters

Personally recommend

 

Average Rating 5.0

Application Area:

Pharma and bio

I really happy to say that we can use highly precise and accurate results we get from this instrument.

Review Date: 14 Apr 2022 | Waters

Great instrument for routine screening of natural products.

 

Average Rating 5.0

Application Area:

Natural products

The instrument is quite robust for the type of application we use it for in drug discovery. It's user friendly and easy to maintain and troubleshoot. Even a new LCMS user would find easy to navigate around.

Review Date: 16 Jul 2021 | Waters

Good alternative to complex and more expensive technologies.

 

Average Rating 4.3

Application Area:

Impurities in pharmaceutical drugs

Good and cheap alternative to more complex mass technologies. Enables low concentration detection of analytes, although it does not provide fragmentation possibilities nor accurate mass.

Review Date: 14 Apr 2021 | Waters

Great equipment.

 

Average Rating 4.7

Application Area:

Analyze GTI in drug substances

Easy to use. Very reproducible. No issues with maintenance. Minimum hands-on training required.

Review Date: 15 Mar 2021 | Waters

Great results.

 

Average Rating 5.0

Application Area:

Pharmaceutical

Excellent service and instruments.

Review Date: 8 Feb 2021 | Waters

Excellent mass detector(mass range: 50-1250 amu).

 

Average Rating 5.0

Application Area:

Discovery chemistry, medchemistry and impurity analysis

Very good product from Waters.

Review Date: 26 Jan 2021 | Waters

This is a great, reliable, easy to use single quad mass spectrometer.

 

Average Rating 5.0

Application Area:

Reaction monitoring, analytical analysis

The Acquity QDa is an easy to use, robust single quad mass spectrometer. It has become an essential tool for our organic medicinal synthesis research for verifying intermediates and final products. It also has been extremely useful for a variety of analytical projects. I find the QDa very easy to use and maintain. It provides reproducible results. We also have a service contract with Waters and they are quick to respond and to repair any problems.

Review Date: 10 Nov 2020 | Waters

The ACQUITY QDa® Mass Detector gives you certainty above all else. You can minimize the risk of unexpected coelutions or components and confirms trace components with the analytical confidence of mass detection.

The ACQUITY QDa® Detector is a mass detector built around the needs of analytical scientists for chromatographic analysis. Robust, reliable and requiring no sample adjustments, it just integrates with your current LC, ACQUITY UPLC, ACQUITY UPC2 and purification systems.

You'll enhance the analytical value and productivity of each analysis, and you won't need to run all the additional assays or time-consuming alternative techniques or even wait for results from specialist labs that cost your laboratory productivity.

With the ACQUITY QDa® Detector, you now have information-rich mass spectral data to complement data from your current Waters® optical detectors, including the ACQUITY UPLC PDA, TUV, ELS, and FLR detectors, as well as the ACQUITY UPC² PDA Detector. This mass spectral information integrates seamlessly into the same workflow; routinely giving you more complete separation characterization.

Features:

  • Intuitive operation
  • More information from every sample
  • Effortless integration
  • Increased efficiency
  • Resolving complexity

Applications:

  • Food & Environment
  • Life Sciences and Pharmaceuticals
  • Chemical

Brochures


Application NoteLife Sciences

Quantification of mono and disaccharides in foods

Monosaccharides fructose, galactose, and glucose, and disaccharides sucrose, lactose, and maltose are common sugar ingredients in foods. This application note demonstrates the accurate and reliable determination of sugar content in food and animal feed samples.


Application NoteFood and Beverage

Analysis of organic acids using a mixed-mode LC column and an ACQUITY QDa Mass Detector

Organic acids (OA) are an important group of compounds for many industries including food and beverages, animal feeds, and human health. Download this application note to see how the performance characteristics of the analytical method, including the limit of quantitation (LOQ), the relationship between the chromatographic peak area and concentration, the precision, and the accuracy have been evaluated.



Application NoteSeparations

Development of a robust method for analysis of aspirin and related substances

In this application note, Waters Corporation presents an MS-compatible method for the analysis of aspirin active pharmaceutical ingredient (API) and its related substances using a Fusion QbD method development software.

Download the full note below to explore how using this software in combination with the ACQUITY Arc System and Empower CDS can enable analytical laboratories to quickly develop reliable and reproducible analytical methods.



The making of a modern biopharmaceutical

In this white paper, Waters Corporation discusses the future trends in the biopharmaceutical industry including multi attribute monitoring (MAM), biophysical analysis as a complement to analytical characterization, and the rise of mass detection as a foundational technology.



Application eBookSpectroscopy

Mass detection: The key to faster biopharma analysis

As the biopharmaceutical industry continues to grow and expand into new and ever more complex modalities, biopharmaceutical developers and manufacturers are in urgent need of optimized analytical solutions. This application-based compendium is intended as a resource for anyone in biopharmaceutical development, manufacturing, and QC who wishes to streamline their drug development, accelerate time-to-market, and enable greater productivity in the laboratory.

Download this eBook to find more about the biopharmaceutical applications of the ACQUITY QDa Mass Detector and the BioAccord system from Waters, including:

  • Increasing specificity and sensitivity in routine peptide analyses
  • LC-UV-MS-based synthetic peptide identification and impurity profiling
  • Improving glycan profiling in process development
  • Monitoring multiple attributes in a single assay
  • Enabling routine & reproducible intact mass analysis when data integrity matters
  • An integrated peptide attribute profiling and monitoring workflow for improved productivity
  • A platform method for the molecular mass analysis of the light & heavy chains of monoclonal antibodies
  • Increasing productivity and confidence for N-linked glycan analysis of biosimilars


Application NoteSeparations

Ensuring food ingredient quality and consistency with a novel mass detection technology

All peppers contain capsaicinoids, the most abundant being capsaicin. In order to improve both data quality and decision making in capsicum extract production, Kalsec’s analytical R&D laboratory developed a new assay for capsaicinoid quantification by implementing a method utilizing ultra-performance liquid chromatography (UPLC®) separation coupled with MS detection. In this application note, Waters presents how this integrated system was comprised of the following technologies: ACQUITY UPLC H-Class System, ACQUITY QDa Mass Detector, and the Empower 3 Chromatography Software.

The practical benefits of the ACQUITY QDa Detector

In this video, meet the ACQUITY QDa Detector, a mass detector built around the needs of analytical scientists for chromatographic analysis. Discover how it’s designed to provide easy access to mass data for non-MS experts and see how simple routine maintenance is performed.


Open Access Analytical Laboratory Provides State-of-the-Art Liquid Chromatography and Mass Spectrometry Technologies for Pharmaceutical and Life Science Researchers

Chris Howson, Open Access Lab Manager, BioCity Laboratory Services, describes the analytical technologies available to scientists working in the pharmaceutical and life science industries at the BioHub, Alderley Park, UK, including Waters ACQUITY QDa® Mass Detector, ACQUITY UPLC® H-Class System and ACQUITY UPC System.


Waters ACQUITY QDa Detector

Watch this video to learn about the ACQUITY QDa Detector from Waters, designed to offer powerful mass detection for analytical chemistry applications.


Waters' ACQUITY QDa Provides Complete Solution for N-Glycan Analysis

Watch this video to hear Rohit Khanna, VP of Marketing at Waters Corporation, describe the demand for complete innovative solutions that maximize efficiency, technology and software capabilities. An example includes fast, easy analysis of N-Glycans without compromising on sensitivity using the ACQUITY QDa system. Such mass spectrometry innovations have now become available to new market areas such as food, environmental and clinical. Interview filmed by SelectScience at Pittcon 2015.


Video

Mass Spectrometry Identifies Food Adulteration

Hear about the history of food adulteration and high-profile scandals. Learn how mass spectrometry is playing a major role in helping food producers and suppliers globally.











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