Status:
Member since: 2017
Organization: AkzoNobel
Good and reliable instrument
Application Area: Performance test
"Easy to use instrument. Gives very high performance when switching to micro cell and capillaries."
Status:
ReviewerMember since: 2017
Organization: Charles university
We are convinced that it is one of the best solution for uhplc analysis today
Application Area:Pharmaceuticals
"Good system for fast and robust analysis. Best sensitivity when coupled to Single Quad mass detector. Very low dead volume that allows working on fast gradient mode. We are users for 1 year, we meet very few problems with it!"
Status:
ReviewerMember since: 2006
Organization: The Scotts-Miracle Gro Co
Great instrument, I like the sensitivity and the limited dead volumes.
Application Area:pesticide analysis
"This is another high quality instrument from Agilent. The drawback is the connection for the front end of the column. It is very fragile and easy to break. The replacement is expensive."
Status:
ReviewerMember since: 2016
Organization: Pfenex
Works great for RP-HPLC, but...
Application Area:SE-HPLC of Biologics
"As a long time Agilent user, I want to contribute a word of caution to those interested in using Agilent UHPLCs for salt-containing mobile phases. Agilent customer service (via phone) was surprised that the installation engineer said it was OK to run salts on the instrument. The small volumes cause the instrument to need a water flush immediately after every run, which is tough in our lab. We now have all UHPLC systems dedicated to RP-HPLC, which works VERY well on these instruments. It is also nice to have the purging integrated into the software, enabling us to fully control the instrument from our remote desktops outside of the lab (think COFFEE!)."
Manufacturer's ResponseThank you indeed for the feedback – it is great to hear you are having a good experience with Reverse Phase experiments on the 1290 Infinity II system. In regards to mobile phases with a high salt content, we do have users around the world running phosphate and other buffers routinely. We at Agilent also run similar types of experiments with robust and reliable results. One approach we have been successful with is to work with users to improve uptime by reducing the concentration of the salts while still maintaining sufficient buffering capacity; one possibility is to work with your local Agilent representatives or the phone support team to see if this is an option for your methods. Thank you very much for your feedback and for your purchase. Please don’t hesitate to contact Agilent if we might be of assistance with this or any other issue.
Status:
ReviewerMember since: 2016
Organization: Noramco
Dependable!
Application Area:Method Development and Analysis of APIs
"Love the Agilent 1290! This instrument works well for HPLC and UHPLC platforms. Easy to transfer methods from a Waters UHPLC to this instrument."
Status:
ReviewerMember since: 2016
Organization: Synergy
Superior system!
Application Area:Toxicology
"The UPLC-MS in our lab is twice as fast as the HPLC-MS. The chromatography also looks better and the instrument runs cleaner."
Status:
Expert ReviewerMember since: 2015
Organization: University of Masachusetts - Amherst
Amazing time saver!!
Application Area:Rapid reversed phase UPLC method development
"We use the 1290 Inifinity to convert exiting RP HPLC methods to UPLC. This has saved us immense amounts of development time and allowed us to return data to clients faster. Agilent continues to provide excellent after care support and OpenLab CDS software is familiar for all."
Status:
ReviewerMember since: 2014
Organization: Merck & Co, Inc.
Good; could be better
Application Area:mAbs (Biologics)
"Use it for analysis of mAbs with various HPLC based applications"
Status:
ReviewerMember since: 2016
Organization: Univ of Alberta
Tremendously improved the quality of the lab outputs
Application Area:Diagnostics
"Cut down run times by 4. Had an excellent after sale service. Compatible with other machines in the lab"
Status:
Advanced ReviewerMember since: 2014
Organization: Boehringer Ingelheim
Achieve great results with high efficiency
Application Area:pharmaceuticals R&D
"Very effective, high efficiency instrument, very robust with high precision. Cuts down analysis time and solvent usage."
Status:
ReviewerMember since: 2010
Organization: US FDA
Application Area:Cosmetics
"The Agilent LC system is great and effective with high quality."
Status:
ReviewerMember since: 2015
Organization: Colgate Palmolive
Application Area:Pharma, FMCG
"It is easy to use, and performance of the system is also excellent. Analysis results are also reliable, good value for money. Hardware is rugged."
Status:
ReviewerMember since: 2014
Organization: Swedish Match
"These LC systems are easy to use and very reliable. We were able to drastically cut analysis time. Agilent instruments are definite workhorse instruments. I would highly recommend. "
Status:
ReviewerMember since: 2015
Organization: lab tecnical
Application Area:Metabolomics
"This system never fails. In the beginning, I found it was difficult to use but I was quickly able to manipulate it very well."
Status:
ReviewerMember since: 2004
Organization: HPLC Method Development
Excellent for method development, robust and good customer support
"Excellent for method development 8 columns, 12 solvents, no baseline noise practically Robust - we use it 4 .5 years without any spare part replacement. When call to support then immediately good and useful response. For cheaper system we spend more money to repair and buy spare parts. "
Status:
Expert ReviewerMember since: 2013
Organization: National Veterinary laboratories
Application Area:bioanalysis
"A good system but not as good as Acquity Waters UPLC or even Shimadzu Nexera. Carry over problems with some sticky compounds and needed to buy an extra module flexicube to get rid of the issue."
Status:
ReviewerMember since: 2013
Organization: University of Pecs
Application Area:Analysis of cavitand derivatives
"It is a very good and very useful instrument. However, the software Masshunter sometimes does not work well. I use this instrument for the analysis of cavitad derivatives."
Status:
ReviewerMember since: 2013
Organization: Dublin City University
Application Area:Pharmaceutical analysis
"Very easy to use, high sample throughput, online degassing and four lines for solvents. Easily made compatible with the software and very easy to use in combination with mass spectrometry. Not much after sales assistance provided so would be beneficial for new users to read a training manual prior to use but very simple to learn how to use through online manual with software. I would recommend to a colleague."
Status:
ReviewerMember since: 2013
Organization: University of Geneva
Application Area:BIOCHEMICAL
"It is easy to use, and well controlled with Analyst from ABSciex. It is easily connected to systems not sold by Agilent. The negative point would be that the Gameboy used to handle it manually for conditioning or column washing should be comprised in the package. The price of this Gameboy seems to be exaggerated to me."
Status:
ReviewerMember since: 2013
Organization: IVM.VU
Application Area:environmental analysis
"I have been working with this Agilent 1290 system for a year and I found it is really user friendly, thus I would strongly recommend the device."
Status:
ReviewerMember since: 2012
Organization: Genentech Inc.
Application Area:Pharmaceutical
"It is very easy to use. I am able to extract data at different wavelengths and to extract ion chromatographs. Also it suggests the structures if I enter the mass which I can correlate with my impurities. We have connected this system with 2D applications and it is very easily manageable and we are able to get the data without changing our methods and can still use buffers like phosphate."
Status:
Advanced ReviewerMember since: 2013
Organization: Ei, LLC
Application Area:Chromatography
"It is one of the highest quality pieces of equipment I have utilized in LC chromatographic analysis. This LC system is a rugged, reproducible, robust system and capable of producing high quality data. As an analytical chemist it is a refreshing experience to work with such sophisticated equipment."
Status:
ReviewerMember since: 2012
Organization: BASF
Application Area:Formulation development of pesticides
"The instrument is robust and rarely breaks down. It is efficient and allows a lot of samples to be analyzed in a short time. The instrument is easy for method transfer, the method can be easily transferred from other instruments (i.e. low pressure HPLC to UHPLC)."
Status:
ReviewerMember since: 2011
Organization: UCB Pharma
"A nice UPLC, very robust."
Status:
ReviewerMember since: 2011
Organization: LEO Pharma
"A good HPLC."
Status:
ReviewerMember since: 2011
Organization: Universidad San Pablo
"A powerful instrument."
Status:
ReviewerMember since: 2011
Organization: Universidad San Pablo
"Really powerful."
Status:
ReviewerMember since: 2011
Organization: Vrije Universiteit Brussel
"A high pressure system giving reliable and precise results."
Status:
ReviewerMember since: 2011
Organization: Vrije Universiteit Brussel
"Robust, reliable performance."