SelectScience
Join Free
NewsSeparations

Waters Launches Progenesis QI Version 2.0 LC-MS Software for Small Molecule Data Analysis at IMSC 2014

10 Sept 2014
Sarah Thomas
Associate Editor

Product news

Waters Corporation introduced Progenesis® QI Version 2.0, the next generation of liquid chromatography-mass spectrometry (LC-MS) software for small molecule 'omics data analysis, at the 20th International Mass Spectrometry Conference in Geneva, Switzerland.

The announcement complements the June introduction of Progenesis QI for proteomics Version 2.0 for large molecule 'omics data analysis. Both Progenesis QI and Progenesis QI for proteomics software take LC-MS data analysis to new levels of speed and sophistication, enabling users to rapidly quantify and identify the significantly changing small molecule, lipid compounds, and proteins in samples.

The new features of Progenesis QI Version 2.0 include Pathway Mapping, which facilitates the process of placing discoveries into a biological context, extracting maximum value from 'omics data; Workflow Automation, which enables the software to move through multiple processing stages without user intervention, thus saving valuable time and allowing for overnight and weekend processing; Improved access to compound databases, increasing the chance of successful compound identification; and seamless integration with the extended statistics functionality in EZInfo 3.0, with two-way dataflow to allow for flexible data mining through a single, menu-driven command.

“Discovery is nothing without understanding,” said Dr. Rohit Khanna, Vice President of Informatics and Worldwide Marketing for the Waters Division. “The new version of Progenesis QI features interface improvements that make working with the software even faster and more intuitive than before, giving users more confidence in their research and a deeper understanding of the results.”

Progenesis QI Version 2.0 provides an easy-to-learn, intuitive workflow that is flexible and based on how researchers function. It has a highly-visual interface. The expanded functionality has broad applications across a wide variety of areas including pharmaceutical, health sciences, food, environmental and chemical research.

Tags

UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Data AnalysisData analysis hardware and software is available to make data processing straight-forward yet powerful. Data software can be used for math and stats, technical graphing and image analysis. In addition, software is available for specific data analysis of electrophoresis, densitometry, ELISA and DNA sequencing.Molecular Recognition SoftwareMolecular recognition software is widely used to analyze DNA, RNA, proteins and chemicals. The software can be useful for graphical viewing, comparative analyses, high-throughput screening, genomics, proteomics and phylogenetics. Molecular recognition software uses bioinformatics tools and analyses such as BLAST searches and generates structural predictions, 3D structures and sequencing information.Software PlatformsSoftware platforms are useful for various stages of laboratory experiments from data collection to data storage and processing. For instance lab software is available for system control, data management, data analysis and qualification / validation.MetabolomicsMetabolomics is the study of small metabolites (the intermediates and products of metabolism). It involves the identification and quantification of cellular metabolites using analytical technologies such as GC, HPLC, NMR, and LC/MS.Data AnalysisThe analysis of data is the process of transforming, modeling and evaluating data to discover useful information from experimental results. LipidsLipids are a diverse group of organic compounds that are insoluble in water, including fats, oils, and hormones. They are critical for cellular structure and energy storage. Explore lipid analysis tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.ProteomicsProteomics refers to the analysis of proteins through a variety of different experiments in order to understand structure and functionality. Typical techniques include protein purification and mass spectrometry.

Related articles

Waters Launches Progenesis QI Version 2.0 LC-MS Software for Small Molecule Data Analysis at IMSC 2014