SPRIworks Fragment Library System III From Beckman Coulter Genomics Automates Library Construction
13 Dec 2010

SPRIworks Fragment Library System III from Beckman Coulter Genomics automates the preparation of libraries for the Life Technologies SOLiD* Sequencer. With the introduction of this third system in a series, researchers can use the SPRIworks system to automate library preparation for the three major next generation sequencing platforms.

Combining Solid Phase Reversible Immobilization (SPRI) chemistry and Beckman Coulter automation, SPRIworks System III facilitates the construction of consistent, quality libraries. Automating the library construction process saves researchers valuable time. One to ten samples can be completed within three and a half hours, and the process provides several size-selection and nick translation options.

Earlier this year, Beckman Coulter Genomics introduced SPRIworks Fragment Library Systems I and II, which automate library preparation for the Illumina Genome Analyzer and the Roche GS FLX** DNA Sequencer, respectively. Like those products, System III utilizes a dedicated, color-coded method card and cartridges. Thus, library construction for all three sequencing platforms can be conducted using one instrument and the appropriate method card and cartridges.

SPRIworks Fragment Library System III is a validated plug-and-play system: users simply insert the method card, samples and adapters; select run options; and press start.

“With the introduction of SPRIworks System III, researchers can automate the construction of libraries for all three major sequencing platforms,” commented Julie Moore, director of marketing for Beckman Coulter Genomics. “Using the same system and processes will increase productivity and provide scientists with the tools for consistent, quality library construction.”

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