New Chromatography Detectors from Varian, Inc. Extend the Range of Universal Detection for HPLC and LC/MS

06 Mar 2008
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Varian, Inc. announced today the release of two new evaporative light scattering detectors (ELSD) for conventional and high speed liquid chromatography. With their universal response, full gradient and solvent compatibility, and excellent baseline stability, Varian ELSDs possess key advantages over conventional UV and RI detectors for busy pharmaceutical and analytical laboratories. In addition, they complement electrospray detection in LC/MS (Liquid Chromatography/Mass Spectrometry) for compounds that are difficult to ionize.

With the capability to deliver sub-ambient evaporation down to 10 °C, the new Varian 385-LC provides maximum sensitivity for compounds with significant volatility below 30 °C, giving it the widest application range of all ELSDs. The new Varian 380-LC is the instrument of choice for non-volatile compounds, including analyses where elevated temperature offers higher sensitivity.

Both instruments offer unrivalled flexibility and sensitivity, delivering a universal response down to the low nanogram range for trace analysis. Real time gas management eliminates solvent effects for constant response across a gradient. Digital data collection enables the detectors to be interfaced with multi-vendor analysis platforms and removes the need for analog to digital interfaces. The new instruments allow chromatographers to save time and improve productivity with on-the-fly adjustment of light source intensity for sample mixtures with a wide concentration range. Excellent reproducibility (± < 2%), greatly enhances productivity. Fast data output rates and extremely low dispersion are ideal for high speed LC, an increasingly important analytical technique.

“These programmable ELSDs provide chemists with unrivalled control of an analysis in real time,” says Martin O'Donoghue, Senior Vice President, Scientific Instruments, Varian, Inc., “Varian’s new 380-LC family of detectors bring sensitive and accurate detection capability to an even wider range of applications.”

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