Delivering 40,000 FSR and 1 ppm mass accuracy, while acquiring at up to 50 full spectra per second, the maXis impact is the instrument of choice for high-throughput test laboratories, many of which are already equipped with UHPLC separations to raise throughput. With remarkable MS/MS sensitivity even at low mass fragments, the maXis impact rivals traditional triple-quad instruments in trace analysis quantitation, while offering all the flexibility and information content of precise-mass assignment and ultra-high resolution at UHPLC speed simultaneously.
"The new maXis impact high sensitivity MS/MS capability boosts our bottom-up proteomics identification rates dramatically," commented Dr. Arnd Ingendoh, Bruker's Director of Proteomics. "Our customers can now dig deeper into the proteome with maXis technology, as well as with complementary techniques, including our class-leading MALDI-TOF/TOF systems, new glycomics tools, MALDI imaging and ETD fragmentation for PTM analysis."
Enhanced bottom-up identification in proteomics by combining complementary technologies will be revealed in detail at Bruker's breakfast workshop at 7:00AM on Monday, June 6th in Room 702 of the Denver Convention Center.
maXisTechnology Explained: Several design advances allow the maXis series to occupy a technology class all of its own, delivering the only simultaneous full sensitivity and high resolution (FSR) specification in the industry. Breaking the 20-year convention where longer TOF flight paths meant loss of sensitivity, the maXis series patented in-flight ion optics refocus ions even during the TOF process itself, and allow the full resolving potential of the long flight path to be utilised, unobstructed by multiple reflectrons or ion beam slicers which all degrade sensitivity significantly. Other high-end Qq-TOF systems may nominally reach high resolution, but only at the expense of a dramatic sensitivity loss suffered by relying on resolution-compensating work-arounds like ion beam slicing, multi-reflectrons, etc. Similarly, designs that use older detection technology to gain speed require signal-discarding devices to artificially 'restore' dynamic range, which destroy the ability to deal with coeluent analytes in complex mixtures.