Screening Environmental Samples for a Diverse Range of Compounds with Accurate Mass LC-MS and an Integrated Scientific Information System

ACQUITY UPLC® HSS (High Strength Silica) T3 Columns contain the first and only 100% silica particle designed, tested and intended for use in applications up to 15000 psi/1000 bar. The ACQUITY UPLC® HSS particle is not an HPLC particle. High pore volume HPLC particles do not possess the mechanical stability necessary to withstand the high column packing and operating pressures of UPLC® separations. The first ligand chemistry in this UPLC®-certified column family utilizes T3 bonding in order to retain and separate polar organic compounds. ACQUITY UPLC® HSS T3 columns possess the superior polar-compound retention, aqueous mobile phase compatibility and ultra-low MS bleed of Atlantis® T3 columns. Easier Method Transfer Since Atlantis® T3 HPLC and ACQUITY UPLC® HSS T3 columns utilize T3 bonding, LC methods can be transferred from HPLC to UPLC® separations. Because Atlantis® and HSS particles are different substrates, some method modification and/or optimization may be required. A compelling benefit of UPLC® technology is the ease and speed at which this method optimization can occur since UPLC® separations offer greater resolution in less time. Moving from XBridge™ HPLC to ACQUITY UPLC® BEH columns is nearly seamless, as the hybrid particle substrates differ only in particle size. However, because of T3 bonding it should be straightforward to make simple adjustments to successfully transfer a separation from an Atlantis® T3 HPLC column to an ACQUITY UPLC® HSS T3 column.

The most powerful solution to the most critical need in separation science today.

The only comprehensive screening solution The Waters® Screening Platform Solution with UNIFI™ is the first and only comprehensive screening solution – target, identify, quantify, and review using a streamlined analytical workflow that enables more accurate results across a wide range of applications.The platform is holistically designed, combining world-class instruments, software, Waters’ Analytical Standards and Reagents, and chemistries. All backed by Waters expert Service and Support.Based on the UNIFI Scientific Information System, the Platform Screening Solution facilitates data standardization so that information can be exchanged and transferred among departments and third-party partners. It enables all laboratory functions to work with a common backbone of analytical information including methods, processed results, and historical data and reports.Screening Platform Solution Includes: ACQUITY UPLC® I-Class System- Increased resolution and reduced peak widths result in unrivalled sensitivity.- Maximizes peak capacity to enhance MS sensitivity.- Provides the lowest carryover, complementing MS sensitivity and extending linear dynamic range.- Maximizes the benefits of sub 2-μm particle columns with the lowest dispersion. Xevo® G2-S QTof- Analyze the broadest range of compounds in the most complex samples. - StepWave™ ion optics allow for unsurpassed levels of robust sensitivity. - Delivers superior UPLC®-compatible mass resolution, matrix-tolerant dynamic range, quantitative performance, mass accuracy, and speed of analysis – simultaneously. UNIFI Scientific Information System- Consolidates state-of-the-art data acquisition, processing, and management capabilities to revolutionize screening processes. - Store, make use of, and share all data, methods, and reports. - UNIFI’s scientific library enables you to make use of your prior work, as well as the data and findings of colleagues. Analytical Standard and Reagents- Precisely formulated, ready-to-use, and will help analysts derive optimal performance from their LC and MS instruments.- Ensure quality and consistency from day-to-day, system-to-system, and lab-to-lab.