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Quantification of Glyphosate and AMPA in Drinking Water

4 Oct 2016

The broad-spectrum herbicide glyphosate is a suspected carcinogen which has led to limit values for glyphosate in drinking water being imposed in many countries. This white paper details separation of glyphosate and AMPA (a metabolite of glyphosate) in the Metrosep Carb 2 separation column using an Ion Chromatography (IC) system consisting of a 940 Professional IC Vario ONE with pulsed amperometric detection (flexIPAD). This method detects very low concentrations and is reliable and inexpensive in comparison to HPLC (High Performance Liquid Chromatography).

940 Professional IC Vario

Metrohm AG

With the 940 Professional IC Vario system, Metrohm sets a new standard in ion chromatography. 940 Professional IC Vario stands for maximum flexibility combined with most easy operation and perfect reliability. Entirely modular by design, the new 940 Professional IC Vario meets your particular requirements while keeping you perfectly flexible. Based on one and the same system, you can configure any IC system you want or need.All solutions – including standards – are produced fully automatically, if desired. Starting with sample injection, the system works completely autonomously. Moreover, it is self- monitoring: All system and method parameters are permanently checked; if any system component should require maintenance, the system tells you so – with a message in plain text.The 940 Professional IC Vario system provides superior reliability of both the system itself and the analytical results produced on it: Because the system is self-monitoring, operator errors are virtually ruled out. You can absolutely rely on your measuring results. Moreover, all results can be traced back to every single step of the analysis and even sample preparation. Thus, even the strictest audits are no reason to worry any more.940 Professional IC Vario Features: Modular high-performance ion chromatography system. Unlimited possibilities for system configuration. Compact dimensions, small footprint. For routine analyses and research applications in the ng/L- to %-range. Highest sensitivity for lowest detection limits. Intelligent system components for reliable results. Wide range of detection options: conductivity, UV/VIS, amperometry, ... Free choice of suppressor and column. All gradient options. Inline eluent preparation integrated in the system. Multi-language MagIC Net software for intuitive and simple operation. Complies with GLP and the FDA regulations. Compatible with the unique and partly patented Metrohm Inline Sample Preparation techniques (MISP). Complete automation for high sample throughput. Low maintenance costs and long lifetime. Rugged Swiss quality.

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Ion ChromatographyIon chromatography, also known as ion exchange chromatography, is a high-performance liquid chromatographic technique used for the separation and identification of ions or polar molecules in a sample, including proteins, nucleotides and amino acids. Equipment includes ion exchange columns, ion exclusion columns, ion chromatography systems, pumps, and detectors. Find the best ion chromatography equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Chromatography Method DevelopmentChromatography method development is the process of designing and optimizing chromatographic techniques to separate and analyze complex mixtures. This includes selecting appropriate stationary and mobile phases, determining flow rates, and optimizing detection methods. Successful method development is essential for high-quality results in fields like pharmaceuticals, food safety, and environmental analysis. Explore chromatography method development tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.HerbicidesChromatographyChromatography is a powerful technique used to separate and analyze components of mixtures based on their chemical properties. It is widely used in fields like biochemistry, pharmaceuticals, and environmental analysis. By exploiting differences in the interaction of substances with a stationary phase and a mobile phase, chromatography enables precise purification and quantification of compounds. Whether you're working with complex biological samples or industrial chemicals, chromatography is essential for obtaining high-quality results. Browse our peer-reviewed product directory to find the best chromatography systems, compare products, read customer reviews, and get pricing directly from manufacturers.Water AnalysisAnalytical methods used to test the purity of drinking water include determining the level of contaminants abides to the level set by the Environmental Protection Agency (EPA).Drinking Water AnalysisAnalytical methods used to test the purity of drinking water include determining the level of contaminants abides to the level set by the Environmental Protection Agency (EPA).