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Fast Detection of Derivatized Drug Samples (Methyl Derivatives) in Spiked Horse Urine Samples Using GC-TOFMS

16 May 2012

Among the most commonly found drugs in horse doping are the non-steroidal anti-inflammatory drugs (NSAIDs): ibuprofen, diclofenac, vedaprofen, indomethacin, and eltenac; and the appetite-enhancer clanobutin which acts on the digestive system and improves the appetite. This note presents the analysis of the methylated drugs using GCTOFMS.

Pegasus® GC-HRT

LECO Corp.

While some systems on the market offer users a choice between acquisition speed or resolution, the Pegasus GC-HRT provides scientists with an unprecedented combination of speed, resolution, mass accuracy, isotopic abundance, and dynamic range. This instrumentation utilizes LECO's own Folded Flight Path™ (FFP™) technology to allow users to achieve resolutions of up to 50,000. LECO's exclusive ChromaTOF-HRT™ software with Automated Peak Find and True Signal Deconvolution® provides seamless data handling and compatibility with the NIST Library.

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Fast Detection of Derivatized Drug Samples (Methyl Derivatives) in Spiked Horse Urine Samples Using GC-TOFMS