ResourceSpectroscopy

Non-Destructive Molecular Profiling of the Skin using Confocal Raman Microscopy

4 Mar 2013

Confocal Raman spectroscopy has been employed as a non-destructive and label-free tool for molecular profiling of the skin. Molecular profiling of the skin is important for cosmetic, dermatological, skin cancer, defense and security research. This application note demonstrates how the inVia Raman microscope from Renishaw can be used to spatially resolve the chemical composition of skin at different depths. Both intrinsic biomolecules of the skin and extrinsic topically applied chemicals were successfully profiled.

inVia Raman microscope

Renishaw plc.

Since being launched, the Renishaw inVia Raman microscope has become the world's best selling research Raman system. The inVia Raman microscope combines simplicity of operation with the high performance and unparalleled flexibility for which Renishaw Raman systems are renowned. inVia Raman microscopes are high-sensitivity systems with integrated research grade microscopes, enabling high resolution confocal measurements. inVia Raman microscopes support multiple lasers, with automatic software switching of excitation wavelength.

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Non-Destructive Molecular Profiling of the Skin using Confocal Raman Microscopy