Analysis of Stem Cell Differentiation Using the Operetta High Content Imaging System
5 Nov 2012

It has been suggested that human mesenchymal stem cells (hMSCs) can be used for tissue engineering and compounds that drive hMSCs to a distinct lineage decision are therefore of great importance. In this application note, the Operetta® High Content Imaging System from PerkinElmer was used to study the cellular changes associated with adipogenic differentiation of hMSCs. The accumulation of intracellular lipid droplets was measured in order to classify cells that had already differentiated into adipocytes. The high content imaging approach allowed for the changes in the actin cytoskeleton, which have been associated with the progressing differentiation of hMSCs, to be determined.

Popular tags in SelectScience

Buying guides

Write a Review

Join the Global SelectScience Community Today! It’s FREE!

Helping you make informed decisions about the latest lab products and technologies:

  • Be the first to learn about new technologies
  • 10,000+ trusted product reviews from your peers
  • Compare 500,000 products and manufacturers
  • Get exclusive buying tips from experts
  • Find solutions fast: 10,000+ Application Notes, Webinars and Videos

Connect with 250,000 scientists... All in one place!

Become a member today!