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Analysis of Amphetamine(s) and Bathsalt Type Drugs in Hair Using SPE and LC-MS/MS

UCT, Inc.
26 Jan 2015

Hair testing can be employed in forensic toxicology laboratories as a basis for documenting chronic or long term exposure to drugs. This poster aims to assist the forensic community by offering analysts in forensic facilities a method that permits small samples of hair to be analyzed for amphetamine and bathsalt (synthetic cathinones) type drugs in a clean format with minimal matrix effects and excellent analytical characteristics in terms of both LC-MS/MS and solid phase extraction.

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Clean Screen® DAU Solid Phase Extraction Columns

UCT, Inc.

Clean Screen® DAU Solid Phase Extraction Column is the flagship product of the forensic solid phase extraction column line. The first product of its kind in the industry, it is a mixed-mode column exhibiting both hydrophobic and cation exchange characteristics. Over 20 years of experience has shown this column to be effective on hundreds of drugs in both the acid-neutral and basic drug categories.

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LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. Solid-Phase ExtractionSolid-phase extraction (SPE) is used for clean-up, extraction and concentration of semi-volatile or non-volatile analytes from complex mixtures including blood, urine and food samples. Multiple formats are available for conducting SPE, including prepacked SPE cartridges, disks and microplates, as well as SPE sorbent powders for manual packing. SPE systems can be used to automate the process and extract multiple samples at once. Solid-phase microextraction (SPME) and supported liquid extraction (SLE) products are also available in the same formats. Find the best SPE, SLE and SPME equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Drugs of AbuseA drug of abuse is a drug that has been taken for non-medical purposes. Such drugs can have mind-altering effects, with some causing dependence and addiction.

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