Separation of Cis and Trans Isomers of Crotamiton using an Acclaim C30 Column

23 Jan 2012

This note describes an efficient and convenient way to determine cis and trans isomers of crotamiton by RP-HPLC for product quality control. The separation was performed on a column using a simple acetonitrile/water mobile phase. The column is designed to provide high shape selectivity for separation of hydrophobic, structurally related isomers and unique selectivity complementary to other RP columns.

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