Analysis of Beta-Blockers Using UPLC with Accurate-Mass Screening

13 Nov 2014

The World Anti-Doping Agency (WADA) includes beta-blockers in its 2014 Prohibited List (Category P2). Recent advances in liquid chromatography and mass spectrometry can help determine the presence of beta-blockers in urine. The Waters Forensic Toxicology Application Solution with UNIFI® enables analysts to confidently screen and identify beta-blocker drugs in urine; data is processed automatically and presented to the user with fully customizable workflows and reports.

Forensic Toxicology Screening Solution with UNIFI

Waters

Purpose-built Solution Achieves Reliable Results with Unparalleled Efficiency and Accuracy The Forensic Toxicology Screening Application Solution with UNIFI delivers the sensitivity, reproducibility, and ease-of-use necessary to perform broad screening techniques on complex biological samples to identify drugs of abuse and other toxicants of interest. Now, for the first time, you will be able to reliably report the presence or absence of toxicological compounds of interest, easily streamline workflows, and increase the speed of analysis for complex matrices using the scientific library functionality and flexible reporting templates.Capture, process and analyze complex high-end mass spectrometry and chromatography data on a single software platform. Gain the ability to test and confirm the presence of compounds in a single measurement. Drastically increase workflow efficiency and improve data review and reporting time with pre-defined workflows. Transform your laboratory with the most innovative screening solution ever built for forensic toxicology testing.Forensic Toxicology Screening Solution with UNIFI Features: Reliably detect and report the presence of drugs and other compounds of interest, while minimizing both false positive and negative results Identify known and unknown compounds with the UNIFI Toxicology Scientific Library Build a historical record of sample analysis data for retrospective review as new challenges emerge Ensure compliance with best-in-class data security and traceability

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Xevo G2-XS QTof

Waters

Xevo G2-XS QTof - eXtreme Sensitivity, eXtraordinary Selectivity, eXceptional Solutions. For the scientist who needs to identify, quantify and confirm the broadest range of compounds in the most complex and challenging samples the Xevo G2-XS QTof provides maximum robustness with no compromise in performance, class-leading real-world quantitative sensitivity, the highest quality, most comprehensive qualitative information, flexibility to adapt to changing needs and is accessible to experts and non-experts alike.

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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. Clinical ChemistryBiochemistry (or clinical chemistry) involves the analysis of bodily fluids using chemical tests. Techniques used include HPLC, chromatography, spectroscopy, mass spectrometry, immunochemical, electrophoresis, turbidometric / spectrophotometric assay, MRI and ISE analysis. Tests are often carried out on plasma or serum but urine (urinalysis) and fecal specimens are also processed.Toxicology / Drugs of Abuse TestingToxicology and Drugs of Abuse Testing is the investigation into toxic and illegal substances found at the scene of a crime or from a suspect and / or victim associated with a scene of a crime. Analyzers, immunoassays and drugs of abuse test kits and presumptive test kits are an essential aspect of toxicology investigation.Beta-BlockersAnti-Doping ScienceAnti-doping science involves the detection of performance-enhancing drugs (PEDs) and banned substances in athletes. This field helps ensure fair competition and athlete safety. Explore anti-doping science tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.