Enantioselective Resolution and Analysis of Chiral Pesticides in Formulations by UltraPerformance Convergence Chromatography (UPC2) with UV Detection
6 August 2015

The study of chiral compounds has been a challenge due to the difficulty in resolving the stereoisomers. Convergence chromatography is a complimentary separation technique to liquid chromatography, providing orthogonal selectivity using supercritical CO2 as the primary mobile phase. This application note demonstrates the enantiomeric and/or diastereomeric resolutions of two pesticides, metalaxyl-M (a phenylamide fungicide) and S-metolachlor (acetanilide class of herbicides), and their analyses in aqueous-based pesticide formulations.