Analysis of Phencyclidine in Urine to U.S. SAMHSA Guidelines with LC/MS/MS and GC/MS
23 Jun 2014
The U.S. Substance Abuse and Mental Health Services Administration (SAMHSA) guideline cutoff level for phencyclidine (PCP) in urine is 25 ng/mL. New guidelines from SAMHSA offer the option of LC/MS/MS as an alternative to GC/MS. This application note describes the use of Agilent Bond Elut Certify mixed-mode solid phase extraction (SPE) for sample preparation in an analysis of PCP by LC/MS/MS and GC/MS.