Size Exclusion Chromatography Products & Reviews

Accelerate early research, development, & release testing of GTx drug substances and products

“Allround“ SEC-columns for initial analysis of unknown samples

EcoSEC Elite and EcoSEC HT GPC/SEC Systems enable efficient polymer characterization

TSKgel GPC columns for organic-soluble polymers are packed with spherical particles composed of polystyrene crosslinked with divinylbenzene (PS-DVB)

MAbPac™ SEC– 1 for Monoclonal Antibody (MAb) Analysis MAbPac™ SEC-1 is a size exclusion chromatography (SEC) column designed for monoclonal antibody (MAb) analysis, including monomers, aggregates, and fragments, under non-denaturing conditions, and in both high- and low-salt mobile phases and volatile eluents.SEC is frequently used because of its simple operating principle and features not found in other sep…

Clarity Chromatography Software Clarity is advanced chromatography data station with software modules for data acquisition, data processing and instrument control. Its wide range of data acquisition interfaces ( A/D converters, LAN, USB, RS232) allows conection to virtually any chromatograph.  The standard set of features can be extended by optional software modules such as GPC, PDA, EA, CE and SST. Clarity Chromatography Sof…

The 1260 Infinity II GPC/SEC System is designed to meet the challenges faced by today’s polymer analysis. This versatile size exclusion chromatography (SEC) and gel permeation chromatography (GPC) system provides accuracy and high performance.

Quickly remove salts and small peptides from large proteins (high MW). Thermo Scientific Zeba Spin Desalting Columns and Plates (40K MWCO) contain a size-exclusion chromatography resin that provides excellent protein desalting performance in a centrifuge format for 5μL to 4mL samples.Zeba Spin Desalting Columns and Plates are polypropylene devices containing a proprietary high-performance size-exclusion resin for effective re…

Preparative PL aquagel-OH columns enable rapid and predictable scale-up for aqueous Size Exclusion and Gel Filtration Chromatography. 

World-class Small Multi Detection GPC System. A refractive index detector is generally used for GPC analysis of hydrophobic polymers. When trace-level additives that have UV absorption are contained in a polymer, both a UV detector and a photodiode array detector, which offers high-sensitivity detection, are used complementarily.By using the Prominence-i (PDA model), LabSolutions workstation, and LabSolutions GPC software (op…

Sugar series columns using dual mode of Ligand Exchange and Size Exclusion Chromatography for specific separation of sugars. Separates mono and di-saccharides by combination of ligand exchange and size exclusion mode Counter ion: Ca2+ (divalent metal ions attached to the packing material separate saccharides from sugar alcohol as these columns retain sugar alcohol strongly.) Only water is required for the analysis (c…

HyperGEL columns are packed with porous polymeric beads with a precise pore size distribution so that solutes are accurately separated according to molecular size.High efficiency HyperGEL columns provide a minimum of 50,000 plates/metre for 5µm particle size. The columns are available for aqueous (HyperGEL AP) or organic (HyperGEL OP) separations.HyperGEL OP columns are offered in 7 pore sizes and 2 particle sizes to test mole…

Developing differentiated polymers and deploying a sustainable operation are two of the utmost challenges facing the polymer and plastics industries. Current GPC/SEC methods are limited by a lack of resolution for novel and complex polymeric entities, the time required to achieve satisfactory separation, and the volume of solvent consumed per analysis. Waters® ACQUITY® Advanced Polymer Chromatography™ (APC™) System is a breakt…

Designed specifically for polymer characterization, the Styragel® columns are grouped into the HR series for low-to-mid molecular weight samples, the HT series for high-temperature applications, and the HMW series for high molecular weight samples. Specifically controlled styrene divinylbenzene formulations provide reproducible performance in your GPC applications.

TOYOPEARL HW-55S resin is a hydroxylated methacrylic polymer for size exclusion chromatography

The 1260 Infinity II High-Temperature GPC System can provide information about all of today’s engineering polymers such as polyolefins, which are one of the most popular polymers with numerous applications. This level of detail helps with development and to predict how a given batch will process and perform in the final product.

Gel Permeation Chromatography (GPC) / Size Exclusion Chromatography (SEC) is the technique used for obtaining a rapid and reliable characterization of polymer molecular weight and molecular weight distribution. Clarity Chromatography Software with GPC Extension provides interactive and automated GPC analysis, including recalibration and GPC reporting, as well as simplifies the retrieval of GPC data. The GPC Extension allows fl…

Economical, high efficiency columns to purify and/or characterize proteins, peptides, and other biomolecules including antibodies, aggregates, and PEGylated proteinsHigh performance: Analytical and preparative BioSep columns offer high resolution, maximum efficiency, and exceptional peak asymmetryImproved recovery: Extremely inert media offers advantages for accurte quantitationFlexible method development: 3 phases options (20…

TSKgel SW-type columns for size exclusion/gel filtration analysis of antibodies and other proteins are silica-based. A hydrophilic diol-type bonded phase shields the silica surface from interacting with protein samples.

Starting with 3 µm ultra-pure silica, Yarra particles are densely bonded with a proprietary surface chemistry. Coupled with tight particle and pore size distribution as well as strict packing and QC specifications, Yarra GFC columns allow for the highest efficiencies and resolution possible. Yarra columns are offered in three phases (SEC-2000, 3000, and 4000), and are ideal for the separation of small to large proteins, as wel…

YMC provides silica-based SEC phases with a dihydroxypropyl modification in 4 different pore sizes.

YMC-SEC MAB is a silica-based size exclusion chromatography column utilizing a dihydroxypropyl stationary phase bonded to a silica gel base, specifically designed for antibody separations.

Developing differentiated polymers and deploying a sustainable operation are a key focus for the polymer and plastics industries. Current GPC/SEC methods are limited by a lack of resolution, separation times, and the volume of solvent consumed per analysis. The ACQUITY Advanced Polymer Chromatography (APC™) System is a breakthrough technology that defines the ultimate in size-based chromatographic separations, delivering more…

These columns provide accurate and precise molecular weight calculations in under 7 minutes! - Fast, accurate and precise molecular weight determinations - Increase sample throughput - Greatly decrease solvent consumption and disposal

The Envirogel high-efficiency GPC cleanup columns are specifically designed to remove low volatility, high molecular weight interferences, such as lipids and natural resins, from environmental samples as specified in EPA Method 3640A. In the past, the cleanup procedure for environmental samples was performed on low-efficiency GPC columns based on packing particle diameters of 37-75 micron (200 to 400 mesh) Bio-Beads S-X resins…