Molecular Characterization of Biotherapeutics: The Agilent 1260 Infinity Multi-Detector Bio-SEC Solution with Advanced Light Scattering Detection
14 September 2015

This application note describes the molecular characterization of two monoclonal antibodies (rituximab) used as biotherapeutics to compare innovator versus biosimilar using the Agilent 1260 Infi nity Multi-Detector Bio-SEC Solution. The molecular weight and size of innovator and biosimilar were found to be comparable.