Achieving Faster GPC Separations Using Novel High Pore Volume Columns from Agilent Technologies and Conventional Instruments
28 Oct 2014
GPC is an important technique for determining the molecular weight distribution of a polymer and for comparing batch-to-batch polymer quality. In common with other liquid chromatographers, GPC users are making more demands on the technique both in terms of speed of analysis and quality of results. The combined requirements for faster size-based separations and the use of conventional instrumentation could be achieved using novel GPC column technology. Columns packed with particles that have a very high pore volume deliver significantly increased resolution compared to a conventional GPC/SEC column set. Run times can be decreased by employing shorter column lengths and higher linear velocities, without sacrificing separation quality. This poster shows the analysis of polymer samples on an Agilent 1260 Infinity GPC/SEC with an RI detector to compare a conventional column set with Agilent PL Rapide and ResiPore columns.