Middle-Down Analysis of Monoclonal Antibody Using Nano-Flow Liquid Chromatography and a Novel Tribrid Orbitrap Mass Spectrometer
21 Jan 2015

This application note demonstrates sensitive analysis of monoclonal antibody using a middle-down approach on a novel Thermo Scientific™ Orbitrap Fusion™ Tribrid™ mass spectrometer. The method combines nano-flow liquid chromatography and complementary higher-energy collisional dissociation (HCD) and electron transfer dissociation (ETD) fragmentation on an Orbitrap Fusion Mass Spectrometer.

Show    per page
1 of 8     Page  1 2 3  ... Next 
Monoclonal Antibody and Related Product Characterization under Native Conditions Using a Benchtop Exactive Plus EMR MS monoclonal antibodies16 Jan 2015Read
Droplet Digital™ PCR: Detection of DNA Methylation digital pcr, DNA methylation7 Jan 2015Read
Pathway Driven Targeted Metabolomics of the Arginine Biosynthesis of Corynebacterium glutamicum metabolomics7 Jan 2015Read
Automation of a Method for the Analysis of a Pain Panel by LC-MS/MS automation6 Jan 2015Read
The Other Microarrays: Detailed Mapping of Humoral Immune Response Using JPT Peptide Technologies' Peptide Microarrays and Tecan Array Technology peptide mapping, post-translational modifications2 Jan 2015Read
Highly Selective Analysis of Steroid Biomarkers Using SelexION™ Ion Mobility Technology biomarker extraction, steroids24 Dec 2014Read
Identification of 1α,25(OH)2-Vitamin D2 and D3 in Serum Samples Using the AB SCIEX Triple Quad™ 5500 System vitamin d, human serum19 Dec 2014Read
High-Throughput Screening of Deubiquitylase Enzyme (DUB) Activity/Specificity and Inhibitor Screening by MALDI-TOF Mass Spectrometry MALDI Imaging17 Dec 2014Read
Automated MAb Workflow: from Harvest Cell Culture to Intact Mass Analysis of Variants monoclonal antibodies, HPLC method development16 Dec 2014Read
Applied Robotics for Enhanced Throughput Options in Microscopy as Demonstrated by Automated Tissue Microarray (TMA) Imaging tissue processing, high throughput16 Dec 2014Read

Popular tags in SelectScience