The VP-ITC system is an ultrasensitive isothermal titration calorimeter designed for ease-of-use. All functions are operated through software to minimize operator involvement and facilitate fast and accurate analyses without the need for expertise in thermodynamics.
The capabilities of ITC as a technique, combined with the unique performance features of the VP-ITC have made this system the best selling ultrasensitive isothermal titration calorimeter in the world.
Characterization of molecular interactions of small molecules, proteins, antibodies, nucleic acids, lipids and other biomolecules.
Assessment of the effect of molecular structure changes on binding mechanisms.
Assessment of biological activity.
More than just affinities: Simultaneous determination of all binding parameters in a single experiment - information unobtainable from more limited binding assays.
Directly measure sub-millimolar to nanomolar binding constants (102 to 109 M-1). Measure nanomolar to picomolar binding constants (109 to 1012 M-1) using the competitive binding technique.
Application versatility: Investigate any biomolecular interaction with high sensitivity.
True in-solution technique: No labeling or immobilization required. No buffer restrictions.
Easily handles turbid solutions.
Easy to use: Unattended operation after sample loading.
Complete system: No additional accessories to purchase. No reagents are required.