TrueSurface Microscopy
True Surface Microscopy - Confocal Microscopy Along with Large Area Optical Profiling WITec´s new True Surface Microscopy option (patent pending) allows confocal Raman imaging guided by surface topography. Confocal microscopy is often desirable due to its suppression of out-of-focus light but can be challenging when analyzing large or rough surfaces. In these cases, only those points that are in focus contribute to the image.…
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Versatile instrument that has been proving its value every day.
Surface characterization and polymer morphology
Excellent instrument that is easy to use and has high resolution. Beside chemical information, it allows for morphology information and height profiling of surfaces. We are very content with the instrument.
Review Date: 20 Jan 2020 | Oxford Instruments Raman
True Surface Microscopy - Confocal Microscopy Along with Large Area Optical Profiling
WITec´s new True Surface Microscopy option (patent pending) allows confocal Raman imaging guided by surface topography. Confocal microscopy is often desirable due to its suppression of out-of-focus light but can be challenging when analyzing large or rough surfaces. In these cases, only those points that are in focus contribute to the image. True Surface Microscopy follows the surface topography with high precision, so that even rough or inclined samples always stay in focus. To achieve this unique capability, the WITec alpha500 series can be equipped with a highly precise sensor for optical profilometry. The topographic coordinates from the profilometer measurement are used to perfectly follow the sample surface in confocal Raman imaging mode. The result is an image revealing chemical properties at the surface of the sample, even if this surface is rough or inclined.
True Surface Microscopy Features:
- Extension for the WITec alpha500 series that combines Large-area surface topography profiling with confocal Raman imaging:
- Topographic confocal Raman imaging
- Topographic large-area Surface imaging
- Topographic spectroscopic imaging
- Unique combination (patent pending) delivers innovative application possibilities for new research techniques
- Ease-of-use through full integration with the alphaControl hardware and WITec Project software environment
- Scan speed up to 2000 pixels/s for rapid data acquisition
- Spatial resolution of 10 - 25 μm laterally and < 100 nm vertically to reveal an expanse of miniscule surface structures
- Light source: High intensity LED for highest throughput, accuracy and longevity
- Measuring distance: 10 mm – 16 mm providing wide-ranging sample size flexibility
- Multi-sensors easily configurable to meet virtually any application
Confocal Raman Imaging, Correlative Raman-SEM, and Atomic Force Microscopy: Geo-Science Applications
Raman spectroscopy has long been applied in geoscience, for example for the identification and characterization of minerals, or in the observation of mineral phase transitions in high- and ultra-high pressure/ temperature experiments. By means of confocal Raman imaging (CRI), such characteristics can be evaluated from large-area scans on the centimeter scale to the detailed investigations with sub-micron resolution. In this study, WITec confocal Raman microscopes of the alpha300 and alpha500 series were used in order to carry out high-sensitivity measurements on a sample of diorite.
Investigations of Pharmaceutical Drug Delivery Systems with Topographic Confocal Raman Imaging
Knowledge about the morphology and chemical composition of heterogeneous materials is crucial for the pharmaceutical development of new material properties for highly specified drug delivery systems. This application note gives an overview of several pharmaceutical dosage forms and drug systems investigated by topographic confocal Raman imaging.
Topographic Confocal Raman Imaging of Archaeological Samples
In archeological research, various specimens such as paintings, mummies, antique objects or fabrics are regularly investigated. Those samples are often unique and require specialized treatment when analyzed. This application note introduces topographic confocal Raman Imaging as a flexible, noninvasive and non-destructive tool for the chemical and molecular characterization of archaeological specimens.
Correlative confocal Raman microscopy
In this video, WITec GmbH explains how correlative Raman imaging microscopy can combine the sensitivity and resolution of 3D chemical characterization with other techniques, and offers an insight into potential applications.
WITec GmbH New Hardware and Software Developments Which Improve User Experience
Visit WiTec at Booth #1638 at Pittcon 2017
