Thermo Scientific T4 DNA Ligase is a single polypeptide. It is commonly used to join DNA molecules to each other. T4 DNA ligase catalyzes the formation of a phosphodiester linkage between DNA chains b...read more
Thermo Scientific T4 DNA Ligase is a single polypeptide. It is commonly used to join DNA molecules to each other. T4 DNA ligase catalyzes the formation of a phosphodiester linkage between DNA chains by condensing the 5'-phosphoryl group of one DNA chain with the adjacent 3'-hydroxyl group of the other DNA chain. T4 DNA ligase will ligate blunt and homologous cohesive ends of double-stranded DNA. It is the only DNA ligase that will efficiently ligate blunt ends in the absence of macromolecular exclusion molecules. T4 DNA Ligase can repair nicks in duplex DNA, RNA or DNA/RNA hybrids. It can also join RNA single strands via bridging oligonucleotide adaptors.
Write a review
Sharing your experience will help scientists like you. Achieve Reviewer Status and Win an iPad air (All reviews published will be entered into the next drawing on May 30th 2014).
Why make an enquiry with SelectScience?
EASY It’s quick and simple to do
FAST Your enquiry will be delivered straight to the manufacturer
FREE You’re under no obligation
SECURE We only pass your details on to trusted suppliers at your request
SAVE TIME Submit your details once and make multiple enquiries