Raptor™ Biphenyl LC Column

Raptor™ Biphenyl LC Column
by Restek Corp.
 4.0/5.0 (1 review)

With Raptor™ LC columns, Restek chemists became the first to combine the speed of superficially porous particles (also known as SPP or “core-shell” particles) with the resolution of highly selective USLC® technology. This new breed of chromatographic column allows you to more easily achieve peak separation and faster analysis times without expensive UHPLC instrumentation. SPP core-shell colum...read more

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AVERAGE RATING: 4.0

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  • 4 out of 5EASE OF USE
  • 4 out of 5AFTER SALES SERVICE
  • 4 out of 5VALUE FOR MONEY

Ian Smith


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Ernest Jackson
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RATING: 4.0

  • 4 out of 5EASE OF USE
  • 4 out of 5AFTER SALES SERVICE
  • 4 out of 5VALUE FOR MONEY




Review date: 27 Jan 2014

Application Area: HPLC Analysis Of Pharmaceuticals
Raptor™ Biphenyl LC Column

"This offers an interesting alternative to C18 and complex mobile phases for some difficult separations. It appears to have advantages over phenyl-hexyl, and with more experience, I may use the Raptor as my generic phase of first choice. It has good efficiency, allowing the possibility of shorter run times. It is well worth investigating for troublesome applications."

Description

 

With Raptor™ LC columns, Restek chemists became the first to combine the speed of superficially porous particles (also known as SPP or “core-shell” particles) with the resolution of highly selective USLC® technology. This new breed of chromatographic column allows you to more easily achieve peak separation and faster analysis times without expensive UHPLC instrumentation.

SPP core-shell columns commonly employ traditional phenyl-hexyl stationary phases, but the innovative Biphenyl ligand, developed by Restek’s chemists, is the next generation of phenyl column chemistry. It provides greater aromatic selectivity than commercially available phenyl-hexyl columns[1] and a greater degree of dispersion than conventional phenyls. As a result, the Raptor™ Biphenyl allows you to more easily separate bioanalytical compounds like aromatics, which elute early or are hard to separate on C18 or other phenyl chemistries.

One of the greatest advantages of an SPP column is the ability to achieve fast, efficient separations by operating at higher linear velocities than are possible with a convbentiaonal fully porous particle column. However this can also result in higher back pressures. Raptor™ columns were designed to handle the increased pressures needed to achieve Selectively Accelerated, and handle it far better than other SPP columns on the market.


Raptor™ Biphenyl LC Column Features & Benefits:

  • Higher efficiency for drastically faster analysis times.
  • Better selectivity for substantially improved resolution.
  • Increased sample throughput with existing HPLC instrumentation.
  • Ideal for bioanalytical testing applications like drug and metabolite analyses.
  • Heightened selectivity and retention for compounds that are hard to resolve or elute early on C18 and other phenyl chemistries.
  • Limits ionization suppression and allows simple, MS-friendly mobile phases.
  • Restek's most popular LC stationary phase applied to Raptor™ SPP core-shell silica.

Column Details:

  • Stationary Phase Category: Phenyl (L11)
  • Ligand Type: Biphenyl
  • Particle: 2.7um SPP
  • Pore Size: 90 Å
  • Surface Area: 150 m2/g
  • Length: 30 - 150 mm
  • ID: 2.1, 3.0, 4.6 mm

Product Overview

Raptor™ Biphenyl LC Column by Restek Corp.
Raptor™ Biphenyl LC Column




  • 4out of 5EASE OF USE
  • 4 out of 5AFTER SALES SERVICE
  • 4 out of 5VALUE FOR MONEY





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