Quattro Premier XE
Developed for your most demanding LC/MS/MS quantitative applications, the Quattro Premier™ XE tandem quadrupole mass spectrometer features the highest levels of sensitivity, selectivity, robustness, speed and accuracy. To maximize the analytical advantages of your ACQUITY UPLC® System, the Quattro Premier XE operates at the highest data acquisition rates. Together, the ACQUITY UPLC® System and the Quattro Premier XE give you i…

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Developed for your most demanding LC/MS/MS quantitative applications, the Quattro Premier™ XE tandem quadrupole mass spectrometer features the highest levels of sensitivity, selectivity, robustness, speed and accuracy.
To maximize the analytical advantages of your ACQUITY UPLC® System, the Quattro Premier XE operates at the highest data acquisition rates. Together, the ACQUITY UPLC® System and the Quattro Premier XE give you industry-leading analytical detection limits, resolution and sample throughput for all of your quantitative applications: Bioanalysis, ADME screening, food safety, environmental monitoring, clinical and more.
Features:
- The best in accuracy and reproducibility of chromatographic peak area measurement
- Robust ZSpray™ atmospheric pressure ionization interface
- Versatile range of ionization options, including multi-mode ionization capability in a single run
- Optional QuanOptimize™ automated instrument optimization and quantitative method development tools
- TargetLynx™ dedicated application managers for your specialized analytical requirements
- Small footprint that sits easily on your laboratory benchtop
Determination of Melamine Residue in Water Samples by UPlC/MS/MS
Since both the drinking water and the food chain may cause a direct or indirect impact on human health, it is important to carry out the study on the analysis method of melamine residue in water samples. This application note describes the determination of melamine residue in water samples using UPLC/MS/MS.
Doping Evaluation with NuGenesis SDMS and TargetLynx
This case study shows how the WADA accredited Doping Control Lab of the Karolinska University Hospital in Stockholm, Sweden, is using Waters systems and software to address the requirements for greater sample throughput and productivity coupled with increased data integrity and accessibility.
Determination of Aconitine in Body Fluids by LC/MS/MS
This note describes a rapid and sensitive method for the quantification of aconitine in biological specimens. The method involves SPE purification prior to analysis using LC/MRM. The utility of the method was demonstrated by its application to authentic samples in 2 fatal cases of suspected aconitine poisoning.
Quantification of Morphine, Morphine-3-Glucuronide and Morphine-6-Glucuronide in Biological Samples by LC/MS/MS
This application note presents a simple method that enables the quantification of morphine in plasma, whole blood and urine. This procedure also allows differentiation between two isobaric glucuronide metabolites.
Quantification of Opiates in Human Urine
This note outlines a LC-MS/MS method developed to allow the simultaneous quantification of several opiates in human urine. The method can be used to establish whether the morphine present has originated from illicit use.
A Comparison of MTS and GUS for Detection and Identification of Drugs in Urine
This note describes a rapid and sensitive method for the simultaneous analysis of haloperidol, risperidone and 9-hydroxyrisperidone. The method involves a simple protein precipitation step prior to analysis with LC/MS/MS and is sufficiently sensitive to enable the quantification of these drugs.
Identifying Contaminants in Food and Environmental Samples
In this video Juan-Vicente Sancho discusses his work at the University Jaume I in Castellon, Spain. Working at the Research Institute of Pesticides and Water, Sancho is involved in the analysis of contaminants/pollutants in environmental and food samples. Using the ACQUITY UPLC systems coupled to mass spectrometers from Waters Corporation more samples can be analyzed in less time with detection of compounds below legislated levels.
















