Thermo Scientific™ Probot MALDI Spotter

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The Probot MALDI spotter is designed for on-line collection of nL- and μL-fractions eluting from nano and capillary LC systems on different types of sample carriers such as MALDI targets, PVDF membranes, 96, 384, or 1536 well plates, or microchip structures. The X,Y,Z-moving table and fixed needle design allow nL-spotting with excellent precision and minimal dead volume.


  • Robotic system for MALDI spotting (and fraction collection)

  • Supports ALDI targets and sample carriers from every vendor

  • Small nL-volumes collection with zero chromatographic dispersion maintaining LC resolution

  • Two well plate (or six AB4700) capacity for collection of more than 4000 spots

  • Integrated reagent (matrix) addition for easy MALDI spotting

  • Dual-collection mode for fraction splitting over two different sample carriers

Typical Probot applications include on-line MALDI target preparation or microfraction collection. Due to its accuracy and flexibility, the Probot is the ideal nano-LC/MALDI-MS interface, integrating the high-sensitivity separation power of nano-LC and high resolving power of MALDI-MS.

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Thermo Scientific™ Probot MALDI Spotter

Manufacturer Thermo Fisher Scientific

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