Operetta High Content Imaging System

Manufacturer PerkinElmer, Inc.   |  Available Worldwide
  |  3 reviews
High Content Imaging System That Simply Works.

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Average Rating: 4.2
3 Scientists have reviewed this product

4 out of 5
Ease of use
5 out of 5
After sales service
4 out of 5
Value for money

Rating: 4.3

"User-friendly software, very easy to setup an acquisition protocol (multi wells, channels, focal positions and time points) The Operetta-Columbus server couple allows users to work remotely and efficiently extract data from the acquired images."

Review date: 17 Jul 2015 | Operetta High Content Imaging System
  • Status:


  • Member since: 2012

  • Organization: LSTM

  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Rating: 4.3
"Good training and after support from Perkin Elmer makes getting a new assay off the ground relatively easy. Once you have learnt how to use the functions a huge amount of results can be obtained."

Review date: 05 Sep 2012 | Operetta High Content Imaging System
  • Status:


  • Member since: 2010


  • Ease of use
    3 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Rating: 4.0

  • Application Area:High Throughput Screening

"Great when it works but has a tendency to be temperamental. Excellent imaging capabilities, the applications seem endless. Used for live cell imaging of autophagy. Plates can be expensive. Need to check that the objective lens is compatible with the plates before starting experiments. Software (Harmony and Columbus) for analyzing results in an unbiased way is great. Perkin Elmer gives great service as well with regular training workshops."

Review date: 30 Aug 2012 | Operetta High Content Imaging System

Operetta High Content Screeng System - High Content Imaging and Analysis That Simply Works.

The Operetta® High Content Imaging System from PerkinElmer is the ideal solution for analyzing the inner workings of healthy and diseased cells. Whether you are performing assay development, genome-wide siRNA, compound screens or looking at a few samples in detail, and whether you are using 3D disease models, primary cells, stem cells, live or fixed cells, the Operetta system delivers all the features you need to generate unbiased, statistically significant data to move your research forward.

And it’s so simple to use that even newcomers to high content imaging and high content analysis can be productive right away.


  • Easily set up assays, automate experiments, analyze data and store, retrieve and present results, making it well suited to a multi-user, multi-department environment.
  • Intuitive Harmony® High Content Analysis Software makes it easy for biologists to turn their biology into unbiased quantitative data.
  • Analysis templates for a range of common applications get new users productive with high content analysis right away.
  • User-configurable image analysis building blocks for easy creation of customized high content analysis applications.
  • PhenoLOGIC™ machine learning option enables you to teach the software to create optimized algorithms for your experiment, segmentation and cell classification.
  • Suitable for a wide range of fixed and live cell applications, with live cell chamber option to maintain environmental conditions (temperature, CO2) to protect your live cell samples.
  • Kinetic capabilities for carrying out time course experiments for a better understanding of cellular dynamics.
  • Fast widefield imaging for routine applications.
  • Confocal imaging option to eliminate background, improve signal-to-noise and protect live cell samples by minimizing photobleaching and phototoxicity.
  • Digital phase contrast for imaging and segmentation of cells that have not been fluorescently labelled.
  • Integrates with robotic automation platforms for a fully automated solution.
  • Expert, global service and applications support from our dedicated team of lab- and field-based application specialists, plus an exclusive HCS support portal.

Assays include:

  • Apoptosis
  • Cell Cycle
  • Cell Differentiation
  • Cell Migration
  • Cell Proliferation
  • Cell Shape Changes
  • Cytotoxicity
  • Neurite Outgrowth
  • Protein Expression
  • Receptor Activation
  • RNAi Screening
  • Signaling Pathway Analysis
  • ...and many more!