LC/MS Effluent Optimizer (LEO)
Optimized LC separation and MS detection – get the best of both worlds.
GERSTEL makes it possible to achieve the perfect LC separation and combine it with the most efficient ionization and lowest achievable MS detection limits for your analytes.
Addition of the GERSTEL LC/MS Effluent Optimizer (LEO) module to your LC/ MS/MS system allow one to take the effluent from the perfect LC separation and then optimize it for MS analysis.
Application examples show sensitivity gains of up to a factor of 40 by simply adding a salt solution to the LC effluent and/or changing its pH.
The LEO module is quickly and easily installed in your LC/MS system.
A solvent mixture, buffer solution or reagent is then easily added to the effluent ensuring that the LC separation can be performed under optimal conditions while also enabling maximum yield in the MS ionization process.
Whether you are looking to perform pH adjustment or post-column derivatization, for method development or routine analysis, when you use LEO and the GERSTEL MAESTRO software you can easily and efficiently control all parameters as part of the overall method. Just one sequence table controls the entire system from sample preparation through LC separation and effluent optimization to MS analysis. It is all done with the click of a mouse.