JASCO Model OR-2090 Chiral Detector has been designed for the detection of optically active compounds such as amino acids, sugars, terpenes, and other compounds containing an asymmetric carbon. In industry, these compounds are widely used as original materials for pharmaceuticals, biochemicals, agro-chemicals, cosmetics, foods, and beverages. It is well known that optical isomers of these compounds often exhibit totally different biological activity. One offers a favorable effect to human body while the other can offer a dangerous or unknown effect. Recently, particularly in the pharmaceutical industry, such optical isomers have to be separated, detected and fractionated in order to investigate the biological activity of each. An HPLC system including a chiral separation column and a chiral detector is essential for such research work. We at JASCO, a world leader in chiro-optical spectroscopy as well as HPLC instrumentation have developed the Model OR-2090 chiral detector for HPLC to meet the demand. The OR-2090 can easily be interfaced with the JASCO HPLC system using the HSS-2000 HPLC System software for Windows2000.