Ion PGM™ Sequencer

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Ion PGM™ Sequencer
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 4.0/5.0 (2 reviews)

Life Technologies

Powered by Ion Torrent™ semiconductor chip technology, the Ion Personal Genome Machine® (PGM™) Sequencer delivers the fastest run times, at the most affordable price, of any next-generation more

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Nicola Normanno


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Member since 2013

National Cancer Inst., Naples
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  • 4 out of 5EASE OF USE
  • 4 out of 5VALUE FOR MONEY

Review date: 03 Jun 2013

Application Area: targeted resequencing
Ion PGM™ Sequencer

"We had a good experience using panel based on Ampliseq technology with the Ion Torrent to detect hot spot mutation in oncogenes and tumor suppressor genes involved in lung and colon tumorigenesis. We were able to detect somatic mutations in samples with low tumor cell percentage (20-30%) with high specificity."

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Marc Ferre


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Member since 2013

University Hospital of Angers
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  • 4 out of 5EASE OF USE
  • 3 out of 5VALUE FOR MONEY

Review date: 25 Mar 2013

Application Area: Sequencing
Ion PGM™ Sequencer

"The Ion PGM Sequencer is an easy to use all-in-a-box instrument, including analysis system. Also, it is a diagnosis capable system. However, the automated prep-system is required and has to be bought separately. This is something I would have liked to have known before buying it."



Powered by Ion Torrent™ semiconductor chip technology, the Ion Personal Genome Machine® (PGM™) Sequencer delivers the fastest run times, at the most affordable price, of any next-generation sequencer. High accuracy, and long reads put the Ion PGM™ Sequencer in a class of its own and makes next-generation sequencing more accessible to scientists around the world.

Powered by fast, simple, scalable semiconductor chips, the Ion PGM Sequencer introduced an entirely new approach to sequencing, making it dramatically faster and more accessible. The new Ion Proton
Sequencer will go even further. With chip densities up to 1,000-fold greater than the Ion PGM™ Sequencer, the Ion Proton Sequencer will put whole-genome sequencing within the reach of any lab.

The Ion Proton Sequencer is based on the next generation of semiconductor sequencing technology that made the Ion PGM™ Sequencer the fastest selling sequencer in the world. New high-throughput chips will enable the Ion Proton Sequencer to sequence a human genome with similar run times, and single-day workflow, as the Ion PGM™ Sequencer.

Data analysis, which has long been a bottleneck for whole-genome sequencing, can also be completed in the same day on a single stand-alone server. In the time it takes for other systems to batch sequence 6 genomes, the Ion Proton Sequencer can sequence and analyze 20 genomes for a small fraction of the cost.

The Ion PGM Sequencer is ideal for sequencing small genomes, sets of genes, or performing gene expression profiling or ChIP-Seq. Using Ion AmpliSeq™. Custom Solutions, researchers can interrogate targeted genomic regions using up to 1,536 amplicons in a single tube, in a single day.

Ion PGM Sequencer users can choose from 3 chip densities for optimal performance for small-genome sequencing, sequencing sets of genes, ChIP-Seq, and gene expression. Ion Proton™ Sequencer users can sequence exomes and whole transcriptomes on the Ion Proton™ I Chip, and human genomes on the higher density Ion Proton™II Chip, with similar run times to the Ion PGM™ Sequencer.


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