Ion Channel Reader 8000 by Aurora Biomed

Manufacturer Aurora Biomed

Ion Channel Reader 8000 by Aurora Biomed product image
Ion Channel Reader 8000

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The Ion Channel Reader 8000 combines flame atomic absorption spectroscopy with microsampling technology to screen against potassium, sodium, calcium, and chloride channels in a medium-throughput format (5000 compounds per day).
Invaluable for ion channel screening, the ICR 8000 - ion channel technology, detects ion channel activity using atomic absorption spectroscopy and flux assays. Current applications include the evaluation of the hERG potassium channel more quickly, more precisely and more accurately than other medium to high throughput ion channel screening systems. Interactions with the hERG channel can lead to prolonged QT syndrome. Thus, regulatory agencies require the assessment of QT liability.
The ICR 8000 displays broad utility; it can be applied to assess both voltage-gated (hERG, BK/SK, Kv1.1, 1.4, 1.5, KCNQ, 2P,etc.) and ligand-gated (KATP, nAChR, etc.) ion channels. This allows researchers to accelerate drug development efforts in the treatment and prevention of diseases associated with ion channels.