The Cartesian Honeycomb from Genomic Solutions^® is an automated bench-top system for simplified setup, storage and visualization of counter diffusion protein crystallization experiments. This user friendly system enables researchers to prepare up to 96 individual counter diffusion crystallization experiments with no manual capillary manipulation. Preparation and reaction assembly takes only minutes. Experimental trays are stored off line and can be easily removed from storage for in-situ analysis on a viewing plate for immediate in situ X-ray diffraction.