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The FastPrep-24™ from MP Biomedicals is the latest evolution of the famous high-throughput sample preparation system from Bio101® Systems, with more than 6,000 installations worldwide, FastPrep® provides a unique means of homogenizing by which any type of sample, no matter how tough, can be quickly and consistently lysed within 40 seconds.

When compared to traditional homogenization methods such as vortexing, syringe shearing, or grinding with a mortar and pestle, the FastPrep-24 homogenizer will save hours of work and provide higher yields of intact DNA, RNA and proteins.

FastPrep-24 uses a unique, optimized motion to disrupt cells through the multi-directional, simultaneous beating of specialized Lysing Matrix beads on the sample material. FastPrep will homogenize up to 24 samples in 2 mL tubes, or with optional adapters, lyse 48 samples in 2 mL tubes, 24 samples in 4.5 mL tubes, 12 samples in 15 mL tubes or 2 samples in 50 mL tubes, either at ambient temperatures, or cryogenically.

A completely self-contained system, FastPrep-24 eliminates the risk of cross-contamination and time consuming clean-up associated with manual lysis methods. Simply add sample and buffers to the Lysing Matrix tube containing specialized beads specific to your application. Homogenization speed and duration times are digitally controlled for consistent results. Upon setting the speed and time with the touch of the a button, simply select this as a memory setting or push “run”, and in less than a minute your samples are completely lysed! The FastPrepR-24 features up to five memory presets for your most frequently used settings.

The unique, vertical angular motion of FastPrep-24 causes the lysing matrix particles to impact the sample from all directions simultaneously, releasing nucleic acids and proteins into the protective buffer faster than with any other system. After centrifugation, the supernatant is collected for further purification processing.


  • Bone, brain, tumors
  • Bacteria gram + or –
  • Yeast, fungi, spores
  • Feces, soil, sediment
  • Leaves, roots, seeds

High performance FastPrep Purification Kits, when used in conjunction with the FastPrep-24 Instrument, provide simple, ready-to-use methods for the release and subsequent purification of intact DNA, RNA, and proteins from virtually any source.

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