Thermo Scientific™ DNAPac® PA100 Nucleic Acid Column

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For n, n-1 Resolution of Single-Stranded Oligonucleotides

The DNAPac® PA100 is a high-resolution anion-exchange column that provides single-base resolution. It is stable under denaturing conditions, rugged, reliable, and can be readily scaled up. The DNAPac PA100 is a 13 μm pellicular, nonporous polymeric resin with bound quaternary amine-functionalized MicroBeads™. The rapid mass-transport characteristics of this resin result in very high-resolution oligonucleotide separations.

The MicroBead resin used in DNAPac columns provides high-resolution separations to ensure maximum peak purity, and makes linear scale-up of your separation easy. For more complex separations, the polymeric properties of the DNAPac PA100 allows great flexibility to select ideal conditions, including high pH, high temperature, or chaotropic agents.

DNAPac® PA100 Nucleic Acid Column Features:

  • Capable of n, n-1 resolution for oligonucleotides
  • Resolves oligonucleotides with secondary structures
  • Compatible with solvent, high pH, and high temperatures
  • Analyzes phosphorothioate-based clinical samples
  • Provides easy scale-up

Column Details:

  • Chemistry: Quaternary amine
  • Particle Size: 13 μm
  • Length: 10, 50, 250 mm
  • ID:  2.0, 4.0, 9.0, 22 mm