The Corning Ultra-Low Attachment surface is a covalently bound hydrogel layer that is hydrophilic and neutrally charged. Since proteins and other biomolecules passively adsorb to polystyrene surfaces through either hydrophobic or ionic interactions, this hydrogel surface naturally inhibits nonspecific immobilization via these forces, thus inhibiting subsequent cell attachment. This surface is very stable, noncytotoxic, biologically inert and nondegradable. The Ultra-Low Attachment surface is useful for: • Growing primary cultures of tumor or normal cells as unattached spheroids • Studying activation and inactivation mechanisms of lymphocytes, monocytes, macrophages and other phagocytic cells • Research and procedures requiring the reduction of eukaryotic or microbial cell attachment • Pre...Read more
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