Chromatrap® uses a solid phase porous polymer functionalised with protein A, allowing the chromatin capture to be more efficient than bead based methods. • Levels of DNA pull down up to 25 times higher than with bead based procedures. • Excellent DNA enrichment with signal to noise ratios typically 2 to 3 times better than competing procedures. • High performance with small sample sizes; as few as 15,000 cells per assay. The Chromatrap® approach is preferable to other methods because: • the use of spin columns negates the use of microbeads • BioVyonTM protein A discs have a proprietary internal structure, composed of pores that have inner surfaces specifically designed to maximise chromatin capture efficiency • the disc base material is chemically inert, reducing incidences of non-specifi...Read more
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