Capto S ImpAct by GE Healthcare

Manufacturer GE Healthcare

Capto S ImpAct by GE Healthcare product image
Capto S ImpAct
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Capto S ImpAct is a strong cation exchange chromatography medium (resin) developed for intermediate purification and polishing of monoclonal antibodies (MAbs) and other biomolecules.

This chromatography medium is part of our platform of high-resolution media based on the Capto product line. The polymeric ligand, in combination with the attributes of the base matrix, gives this cation exchanger a high binding capacity. Furthermore, the small bead size enables high-resolution purifications.

The high-flow characteristics of Capto media allows for excellent pressure-flow properties. The exceptional binding capacity and resolution of Capto S ImpAct, combined with the ability to run at high flow rates and bed heights, increase productivity and flexibility in process design.

Capto S ImpAct is a BioProcess chromatography medium developed for large-scale purification of biopharmaceutical proteins. Based on the well-established Capto base matrix, it provides many opportunities for improved productivity and straightforward process development.

Capto S ImpAct is available in a range of different bulk pack sizes and convenient prepacked formats for easy scale-up and process development. As a member of the BioProcess media range, Capto S ImpAct meets industrial demands with security of supply and comprehensive technical and regulatory support.


  • High binding capacity, > 100 mg MAb/mL medium.
  • Efficient aggregate removal at high load of monoclonal antibodies.
  • High-resolution intermediate purification and polishing based on the well-established Capto platform.
  • Flexibility of design thanks to a large operational window of flow rates and bed heights for easy optimization and scaling.
  • High productivity enabling cost-efficient manufacturing.
  • Security of supply and comprehensive regulatory support.