- Ease of use
- After sales service
- Value for money
Description
The 4000 QTRAP® LC/MS/MS System is AB SCIEX's premier Hybrid Triple Quadrupole/Linear Ion trap mass spectrometer. Ideal for drug discovery and development, metabolite identification, contaminant testing, and proteomic applications including post-translationally modified proteins discovery, protein identification, and biomarker validation.
Features of the 4000 QTRAP® LC/MS/MS System:
- Enables high-sensitivity full-scan MS, MS/MS, and MS3 with high-selectivity from true triple quadrupole precursor ion (PI) and neutral loss (NL) scans.
- Perform multiple reaction monitoring (MRM) for quantitation using high-sensitivity triple quadrupole.
- Identify, characterize, and quantitate metabolites more quickly and easily.
- Identify and sequence post-translationally modified (PTM) peptides automatically in a single LC/MS/MS run.
- Facilitates hypothesis-driven biomarker discovery and validation.
Application notes and news
- Advanced Automated Library Searching for Compound Identification in Forensic Toxicology Samples
- MRM3 Quantitation for Highest Selectivity in Complex Matrices
- High Throughput Metabolic Stability Screening with MALDI Triple Quadrupole Mass Spectrometry
- An Automated High Throughput Approach to Permeability Screening using MDCK Monolayers and Rapid LC/MS/MS An...
- Strategies to Identify and Confirm Phase I Metabolites of Glyburide Using the 4000 Q TRAP™ System
- Workhorse Mass Spectrometer for Routine Quantitation and Screening
Reviews
Danielle West Status: See all reviews Member since 2013 Organization: Missouri University of Science and Technology Read more » | RATING: 3.7 
"I utilize the AB sciex 4000 Qtrap on a daily basis, in an LC-MS set up. This instrument set up for easy set up and ran by beginners. This was my first MS to ever run solo, and it was quick to pick up and utilize with the software. We utilize this set up for water research and it works great. It also requires minimal maintenance."   |
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| Manish Kumar Status: See all reviews Member since 2010 Organization: Panacea Biotec Ltd. Read more » | RATING: 4.6
"The system shows excellent sensitivity but is not that reproducible. It is very rugged and provides excellent value for money." |
| Tao Ye Status: See all reviews Member since 2010 Organization: Massachusetts Institute of Technology Read more » | RATING: 4.6
"Easy to use and maintain and good value. Reliable hardware, delivers the results you expect. The software is ok but not stable. It freezes very frequently but easy to use." |
| Raji Ravi Status: See all reviews Member since 2009 Organization: Dept. of Health and Mental Hygiene, Maryland Read more » | RATING: 5.0
"Reliable, user friendly software. Good, friendly on-site tech support." |
| Greta Moraes Status: See all reviews Member since 2008 Organization: ANSTO Read more » | RATING: 4.0
"The mass spectrometer has very high sensitivity and the analyst software is very user friendly." |
| Gilbert Moachon Status: See all reviews Member since 2005 Organization: Cephalon France Read more » | RATING: 4.3
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| Navnath Jaybhaye Status: See all reviews Member since 2007 Job Title: Research Scientist / Senior / PI Discipline: ADME / DMPK Work Field: Pharmaceuticals / Biopharmaceuticals Organization: Bio Analytical Technologies India (P) Ltd Read more » | RATING: 4.6
"Very nice instruments for bioanalysis, impurity identification, metabolite identification and charcterisation." |
| Prabhakar Gruddanti Status: See all reviews Member since 2011 Organization: Emory Institute for Drug Discovery Read more » | RATING: 3.6
"The software is poorly designed." |
| Wale Rufai Status: See all reviews Member since 2010 Organization: Amgen Read more » | RATING: 5.0
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| Wale Rufai Status: See all reviews Member since 2010 Organization: Amgen Read more » | RATING: 5.0
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| Dayanjan Wijesinghe Status: See all reviews Member since 2009 Organization: Virginia Commonwealth University Read more » | RATING: 4.6
"A great product." |
| David Herold Status: See all reviews Member since 2009 Organization: Mass Spectrometry Applications to the Clinical Laboratory Read more » | RATING: 4.3
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| Manjula Sunkara Status: See all reviews Member since 2009 Organization: University of Kentucky Read more » | RATING: 4.0
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| Jeff Morre Status: See all reviews Member since 2009 Organization: Oregon State University Read more » | RATING: 4.3
"A work horse of an instrument." |
| René Zahedi Status: See all reviews Member since 2008 Organization: Rudolf Virchow Center For Experimental Biomedicine Read more » | RATING: 3.6
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| MIN KANG Status: See all reviews Member since 2008 Organization: CHILDRENS HOSPITAL LOS ANGELES-USC Read more » | RATING: 3.6
"an excellent system for lipidomics, but it does require training and is quite pricey." |
| Guowang Xu Status: See all reviews Member since 2006 Organization: Dalian Institute of Chemical Physics Read more » | RATING: 4.0
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| Blanka Toth Status: See all reviews Member since 2007 Organization: Budapest University of Technologies Read more » | RATING: 3.6
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| Borislav Starcevic Status: See all reviews Member since 2004 Organization: UCLA Olympic Analytical Laboratory Read more » | RATING: 3.6
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| Wayne Mullett Status: See all reviews Member since 2006 Organization: Merck Frost Read more » | RATING: 4.0
"Excellent instrument and sensitivity." |
| Xiaoli Wang Status: See all reviews Member since 2005 Organization: Pfizer Read more » | RATING: 3.3
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