Roche Launches New MagNA Pure 96 System: A Perfect Combination of Performance and High Throughput

The Roche LightCycler 480 System - Another breakthrough in real-time PCR analysis of gene expression and melting curve-based mutation analysis.The Roche LightCycler 480 RT-PCR System combines amazing speed with exceptional accuracy and will meet the needs of a broad range of scientific applications in genomics research including array validation, gene-knockdown studies, and SNP analysis.This Roche Light Cycler PCR supports all current probe formats and applications and its built-in versatility allows adaptation to future technological advances in genomics research.Customer benefits from the Roche LightCycler® 480 System: Speed – rapid temperature control for superb specificity and yield.The LightCycler 480 PCR System utilizes a novel block technology to allow the rapid heating and cooling required to complete a 40-cycle, 384-well quantitative PCR run in less than 40 minutes and leads to extraordinary well-to-well temperature homogeneity and maximized inter-well, inter-cycle reproducibility. Accuracy – unbiased conditions for unambiguous results Special arrangement of optical components ensures the uniform collection of signals across the plate and makes analysis independent of sample position or differences in reaction volume. Versatility – utmost flexibility for maximum efficiency Five excitation and six emission filters of the Roche LightCycler allow you to work with the assay format of your choice, including SYBR Green I, hydrolysis probes, probes, probes, Molecular Beacons, and others. High-performance optical system from the LightCycler 480Fluorescence excitation by a high-intensity xenon lamp, and a specially developed signal-collection system, result in maximal sensitivity for any assay format in all channels. Additional Features of the LightCycler 480 PCR System: Customizable modular system concept Building on the principles of the well-established, performance-proven LightCycler® Software 4.0, the Roche LightCycler® 480 platform comes equipped with modules for run control, Tm calling, and absolute quantification. Further customize your system to your specific needs by adding separately offered advanced analysis modules. Especially developed reagents A tailor-made hot-start PCR enzyme master mix is available for each type of LightCycler® 480 application. Built on Roche Diagnostics’ performance proven FastStart technology, these reagents ensure optimal reproducibility and high dynamic ranges. Perfect integration into laboratory workflow Compatibility for automated sample-preparation, automated loading and connectivity to laboratory information management systems (LIMS) for integrated workflow monitoring offer uncompromising adaptability for a perfect fit.

The MagNA Pure 96 System from Roche Applied Science has been designed and engineered to meet the needs for high throughput laboratories worldwide. The integrated system enables batch processing of up to 96 samples in parallel ensuring every sample is treated exactly the same while providing extremely quick turnaround time. These characteristics result in a low sample processing time; for typical standard applications, 96 samples can be completely processed with the fully automated MagNA Pure 96 System in less than one hour, including instrument setup. Additionally, prefilled reagent kits and disposables from Roche enable a convenient, safe, and fast setup of purification runs. The new MagNA Pure 96 System offers a broad field of applications, including isolation of DNA, RNA, and viral nucleic acid. It can be used with various research sample materials such as mammalian whole blood, cells, plasma, serum, PAXgene tubes, or tissue. Sample input volumes range from 50–1000 μl to enable maximum flexibility in respect to the individual needs of yield and sensitivity. The data management is facilitated by the flexible connectivity features, with an optimized data workflow, when used in combination with the LightCycler® 480 System.