Syngene, a world-leading manufacturer of image analysis solutions, is pleased to announce two of its G:BOX multi-application imaging systems have shown excellent performance with SuperArray Bioscience’s Oligo GEArrays®, offering researchers a precise method of characterizing gene expression.
New Chemiluminescent Application of G:BOX Image Analyzers Makes Accurate Imaging of Microarrays Accessible to all Laboratories
Researchers at the leading array manufacturer, SuperArray Bioscience, have evaluated their Oligo GEArrays using the G:BOX Chemi HR16 and G:BOX Chemi XT16 imaging systems. They found using a G:BOX Chemi HR16, they could image eight arrays simultaneously and with the G:BOX Chemi XT16, 32 arrays at the same time. They also showed both systems had excellent dynamic range and their cooled cameras allowed the long exposure times of 20 minutes often required to get maximum signal, with low background noise on the resulting images.
Dr Ray Blanchard, Senior Scientist, at SuperArray Bioscience explained: "Many researchers use X-ray film, followed by scanning and densitometry to analyze chemiluminescent microarrays, but by doing this, they can lose around 80 percent of the information just in the handling. Using the right CCD based system scientists can capture much more data, producing quantitative analysis and, as a result, reliable gene expression measurements.”
Dr Blanchard continued: “Not all CCD based analyzers can image arrays, and we have a check list of criteria these systems must meet before they are recommended for imaging Oligo GEArrays. Both the G:BOX Chemi XT16 and G:BOX Chemi HR16 successfully meet all our requirements, not only on paper, but also during our tests to generate high quality images of Oligo GEArrays.”
Paula Maia, Vice President of Sales, Syngene US concluded: "We are delighted to see our systems performing well in this important application because it shows that any laboratory can confidently harness the powerful combination of Oligo GEArrays and G:BOX systems to deliver accurate gene expression results every time.”