Product News: Now Get More Results with Less Sample

24 Aug 2007

Researchers can now achieve gold standard binding affinities with only 200 μl of sample in the new iTC200 Isothermal Titration Calorimeter from MicroCal. The iTC200 determines all binding parameters both label free and without the need for immobilization, using as little as 5 to 10 µg of protein. Requiring no assay development or dedicated user, the unit is designed to address the needs of drug discovery and development in such applications as hit selection, lead optimization and binding characterization. With its reduced size and associated sample requirements, the iTC200 is the fastest Isothermal Titration Calorimeter available on the market.

The iTC200 is controlled by an intelligent user interface that assists in experimental design and processes data at the end of sample runs. Results are presented in an Excel format for further analysis or data transfer. For researchers currently working with the MicroCal VP-ITC, which has become the standard in isothermal titration calorimetry, the new iTC200 provides the same high quality data two to four times faster using seven-fold less sample volume and up to seven-fold less sample material. As an added advantage for those requiring higher throughput, the iTC200 can be easily upgraded to the fully automated Auto-iTC200, which is capable of running up to 50 samples a day and 384 samples unattended.