DiscoveRx PathHunter™ eXpress Kits and GPCR Profiling Services: GPCR Research Made Simple

11 Sept 2008

Product news

DiscoveRx announces the launch of PathHunter™ eXpress β-Arrestin assay kits for use with chemiluminescent microplate readers as well as Caliper® LabChip microfluidics platform. PathHunter™ β-Arrestin assay detects binding of an agonist to a GPCR of interest by directly measuring β-arrestin binding to the activated GPCR. With a broad panel of receptors available as ready to go GPCR kits, GPCR profiling and research is easier and simpler than before. No need to send out compounds for profiling. Use of the pre-validated eXpress β-Arrestin cell kits eliminates the requirement for cell culture and enables profiling on multiple targets in minimal time at your site!

For those who prefer to have the analysis done by DiscoveRx, we offer a wide variety of profiling and screening services for selectivity screening, secondary screening and SAR. With the ability to detect unique pharmacology using PathHunter Arrestin technology, you will be getting valuable information about drug efficacy and specificity outside of traditional assay formats. Come meet us at ELRIG show Booth number (H01) and discuss your GPCR needs. Be the first 50 visitors to our booth to receive a gift and register to win exciting prizes.

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High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Automation Supplies / AccessoriesAutomated accessories and consumables make lab processes fast, efficient and reliable. Useful automation accessories include microplate sealers, label printers and reagent reservoirs.